Tissue expression of NELFCD - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	NELFCD
Gene description	Negative elongation factor complex member C/D
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	NELFCD (HGNC Symbol)
Synonyms	HSPC130, NELF-C, NELF-D, TH1, TH1L
Description	Negative elongation factor complex member C/D (HGNC Symbol)
Entrez gene summary	The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini. [provided by RefSeq, Jul 2008]
Chromosome	20
Cytoband	q13.32
Chromosome location (bp)	58981208 - 58995133
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101158 (version 83.38)
Entrez gene	51497
UniProt	Q8IXH7 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IXH7
Antibodypedia	NELFCD antibodies

PROTEIN BROWSER

NELFCD-003	NELFCD-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NELFCD-003 ENSP00000473290 ENST00000602795	H0UI80 [Direct mapping] Negative elongation factor C/D; TH1-like (Drosophila), isoform CRA_b Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0045892 [negative regulation of transcription, DNA-templated] Show all	599 aa 67.3 kDa	No	0
NELFCD-201 ENSP00000342300 ENST00000344018	Q8IXH7 [Direct mapping] Negative elongation factor C/D Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0032021 [NELF complex] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0050434 [positive regulation of viral transcription] Show all	473 aa 52.4 kDa	No	0