Fields »
ABOUT
HELP
BLOG
NTSR1

GENERAL INFORMATION

Gene name

 NTSR1

Gene description

 Neurotensin receptor 1 (high affinity)

Protein class

 G-protein coupled receptors
Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Not detected
GTEx:Tissue enriched (colon)
FANTOM5:Tissue enhanced (colon, appendix)

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (colon)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (colon, appendix)

GENE INFORMATION

Gene name

 NTSR1 (HGNC Symbol)

Synonyms

 NTR

Description

 Neurotensin receptor 1 (high affinity) (HGNC Symbol)

Entrez gene summary

 Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008]

Chromosome

 20

Cytoband

 q13.33

Chromosome location (bp)

 62708837 - 62762771

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000101188 (version 83.38)

Entrez gene

 4923

UniProt

 P30989 (UniProt - Evidence at protein level)

neXtProt

 NX_P30989

Antibodypedia

 NTSR1 antibodies

PROTEIN BROWSER
NTSR1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NTSR1-001
ENSP00000359532
ENST00000370501
P30989 [Direct mapping]
Neurotensin receptor type 1
Show all
Transporters
G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001659 [temperature homeostasis]
GO:0003085 [negative regulation of systemic arterial blood pressure]
GO:0003254 [regulation of membrane depolarization]
GO:0004930 [G-protein coupled receptor activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007218 [neuropeptide signaling pathway]
GO:0007268 [synaptic transmission]
GO:0007612 [learning]
GO:0008344 [adult locomotory behavior]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0009986 [cell surface]
GO:0014049 [positive regulation of glutamate secretion]
GO:0014054 [positive regulation of gamma-aminobutyric acid secretion]
GO:0016021 [integral component of membrane]
GO:0016492 [G-protein coupled neurotensin receptor activity]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0032280 [symmetric synapse]
GO:0033993 [response to lipid]
GO:0042803 [protein homodimerization activity]
GO:0043025 [neuronal cell body]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043195 [terminal bouton]
GO:0043197 [dendritic spine]
GO:0043198 [dendritic shaft]
GO:0043204 [perikaryon]
GO:0043576 [regulation of respiratory gaseous exchange]
GO:0043679 [axon terminus]
GO:0044309 [neuron spine]
GO:0045121 [membrane raft]
GO:0045202 [synapse]
GO:0046982 [protein heterodimerization activity]
GO:0047485 [protein N-terminus binding]
GO:0050965 [detection of temperature stimulus involved in sensory perception of pain]
GO:0051280 [negative regulation of release of sequestered calcium ion into cytosol]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051930 [regulation of sensory perception of pain]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070779 [D-aspartate import]
GO:0071545 [inositol phosphate catabolic process]
GO:0090238 [positive regulation of arachidonic acid secretion]
GO:0097151 [positive regulation of inhibitory postsynaptic potential]
GO:0098900 [regulation of action potential]
GO:1990123 [L-glutamate import into cell]
GO:2001259 [positive regulation of cation channel activity]
Show all
 418 aa
46.3 kDa 		No 7

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.