Cell atlas - SLC17A9 - The Human Protein Atlas

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SLC17A9

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	SLC17A9
Gene description	Solute carrier family 17 (vesicular nucleotide transporter), member 9
Protein class	Disease related genes Potential drug targets Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Cell line enhanced (Hep G2, U-937)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA047470
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (Hep G2, U-937) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA047470	CACO-2	Nucleoplasm
	HPA047470	Hep G2	Nucleoplasm
	HPA047470	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	SLC17A9 (HGNC Symbol)
Synonyms	C20orf59, FLJ23412, VNUT
Description	Solute carrier family 17 (vesicular nucleotide transporter), member 9 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of transmembrane proteins that are involved in the transport of small molecules. The encoded protein participates in the vesicular uptake, storage, and secretion of adenoside triphosphate (ATP) and other nucleotides. A mutation in this gene was found in individuals with autosomal dominant disseminated superficial actinic porokeratosis-8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Chromosome	20
Cytoband	q13.33
Chromosome location (bp)	62952647 - 62969585
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101194 (version 83.38)
Entrez gene	63910
UniProt	Q9BYT1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BYT1
Antibodypedia	SLC17A9 antibodies

PROTEIN BROWSER

SLC17A9-001	SLC17A9-002	SLC17A9-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC17A9-001 ENSP00000359376 ENST00000370351	Q9BYT1 [Direct mapping] Solute carrier family 17 member 9 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0005215 [transporter activity] GO:0005623 [cell] GO:0006820 [anion transport] GO:0006887 [exocytosis] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:1903146 [regulation of mitophagy] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	436 aa 47.5 kDa	No	>9
SLC17A9-002 ENSP00000388215 ENST00000411611	Q5W197 [Direct mapping] Solute carrier family 17 member 9 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0006820 [anion transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	152 aa 16.7 kDa	No	4
SLC17A9-007 ENSP00000359374 ENST00000370349	Q9BYT1 [Direct mapping] Solute carrier family 17 member 9 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0005215 [transporter activity] GO:0005623 [cell] GO:0006820 [anion transport] GO:0006887 [exocytosis] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:1903146 [regulation of mitophagy] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	430 aa 46.8 kDa	No	>9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.