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ADNP2

GENERAL INFORMATION

Gene name

 ADNP2

Gene description

 ADNP homeobox 2

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in selected tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA007126
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ADNP2 (HGNC Symbol)

Synonyms

 KIAA0863, ZNF508

Description

 ADNP homeobox 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 18

Cytoband

 q23

Chromosome location (bp)

 80109031 - 80147523

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000101544 (version 83.38)

Entrez gene

 22850

UniProt

 Q6IQ32 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6IQ32

Antibodypedia

 ADNP2 antibodies

PROTEIN BROWSER
ADNP2-001
ADNP2-002
ADNP2-003
ADNP2-004
ADNP2-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ADNP2-001
ENSP00000262198
ENST00000262198
Q6IQ32 [Direct mapping]
ADNP homeobox protein 2
A0A024R377 [Target identity:100%; Query identity:100%]
KIAA0863 protein, isoform CRA_a
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
   Helix-turn-helix domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0030182 [neuron differentiation]
GO:0030307 [positive regulation of cell growth]
GO:0034599 [cellular response to oxidative stress]
GO:0046872 [metal ion binding]
GO:0060548 [negative regulation of cell death]
GO:0071300 [cellular response to retinoic acid]
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 1131 aa
122.8 kDa 		No 0
ADNP2-002
ENSP00000453275
ENST00000559951
H0YLN6 [Direct mapping]
ADNP homeobox protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 171 aa
19.9 kDa 		No 0
ADNP2-003
ENSP00000453418
ENST00000560752
H0YM09 [Direct mapping]
ADNP homeobox protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 229 aa
26.7 kDa 		No 0
ADNP2-004
ENSP00000468397
ENST00000560561
K7ERT3 [Direct mapping]
ADNP homeobox protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 82 aa
9.1 kDa 		No 0
ADNP2-005
ENSP00000467370
ENST00000561195
K7EPG1 [Direct mapping]
ADNP homeobox protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 26 aa
2.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.