Expression of SMCHD1 in cancer - Summary

CANCER ATLAS

Gene description

Structural maintenance of chromosomes flexible hinge domain containing 1

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039441

GENE INFORMATION
Gene name	SMCHD1 (HGNC Symbol)
Synonyms	KIAA0650
Description	Structural maintenance of chromosomes flexible hinge domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which contains a hinge region domain found in members of the SMC (structural maintenance of chromosomes) protein family. [provided by RefSeq, Dec 2011]
Chromosome	18
Cytoband	p11.32
Chromosome location (bp)	2655738 - 2805017
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101596 (version 83.38)
Entrez gene	23347
UniProt	A6NHR9 (UniProt - Evidence at protein level)
neXtProt	NX_A6NHR9
Antibodypedia	SMCHD1 antibodies

PROTEIN BROWSER

SMCHD1-001	SMCHD1-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SMCHD1-001 ENSP00000326603 ENST00000320876	A6NHR9 [Direct mapping] Structural maintenance of chromosomes flexible hinge domain-containing protein 1 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001740 [Barr body] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005694 [chromosome] GO:0009048 [dosage compensation by inactivation of X chromosome] GO:0051276 [chromosome organization] GO:0060821 [inactivation of X chromosome by DNA methylation] Show all	2005 aa 226.4 kDa	No	0
SMCHD1-015 ENSP00000463036 ENST00000583800	J3KTK7 [Direct mapping] Structural maintenance of chromosomes flexible hinge domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		48 aa 5.4 kDa	No	0