Tissue expression of CEP76 - Summary - The Human Protein Atlas

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CEP76

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CEP76
Gene description	Centrosomal protein 76kDa
Protein class	Cancer-related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Granular cytoplasmic expression in several tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA039395
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	CEP76 (HGNC Symbol)
Synonyms	C18orf9, FLJ12542, HsT1705
Description	Centrosomal protein 76kDa (HGNC Symbol)
Entrez gene summary	This gene encodes a centrosomal protein which regulates centriole amplification by limiting centriole duplication to once per cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Chromosome	18
Cytoband	p11.21
Chromosome location (bp)	12661833 - 12702777
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101624 (version 83.38)
Entrez gene	79959
UniProt	Q8TAP6 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TAP6
Antibodypedia	CEP76 antibodies

PROTEIN BROWSER

CEP76-001	CEP76-003	CEP76-010	CEP76-011	CEP76-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CEP76-001 ENSP00000262127 ENST00000262127	Q8TAP6 [Direct mapping] Centrosomal protein of 76 kDa Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000278 [mitotic cell cycle] GO:0005515 [protein binding] GO:0005813 [centrosome] GO:0005814 [centriole] GO:0005829 [cytosol] GO:0006996 [organelle organization] GO:0043234 [protein complex] GO:0046599 [regulation of centriole replication] Show all	659 aa 74.4 kDa	No	0
CEP76-003 ENSP00000403074 ENST00000423709	Q8TAP6 [Direct mapping] Centrosomal protein of 76 kDa Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000278 [mitotic cell cycle] GO:0005515 [protein binding] GO:0005813 [centrosome] GO:0005814 [centriole] GO:0005829 [cytosol] GO:0006996 [organelle organization] GO:0043234 [protein complex] GO:0046599 [regulation of centriole replication] Show all	584 aa 65.7 kDa	No	0
CEP76-010 ENSP00000467224 ENST00000585751	K7EP44 [Direct mapping] Centrosomal protein of 76 kDa Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Ezkurdia et al 2014) Show all		191 aa 21.8 kDa	No	0
CEP76-011 ENSP00000467361 ENST00000591034	K7EPF5 [Direct mapping] Centrosomal protein of 76 kDa Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Ezkurdia et al 2014) Show all		101 aa 11.6 kDa	No	0
CEP76-012 ENSP00000464911 ENST00000587666	K7EIV8 [Direct mapping] Centrosomal protein of 76 kDa Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Ezkurdia et al 2014) Show all		178 aa 19.8 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.