Tissue expression of POLI - Summary - The Human Protein Atlas

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POLI

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TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	POLI
Gene description	Polymerase (DNA directed) iota
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in several tissues. Highly expressed in testis.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. External characterization data supports antibody staining.
Reliability score	Supported based on 1 antibody. HPA064696
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

N/A

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	POLI (HGNC Symbol)
Synonyms	RAD30B, RAD3OB
Description	Polymerase (DNA directed) iota (HGNC Symbol)
Entrez gene summary
Chromosome	18
Cytoband	q21.2
Chromosome location (bp)	54269404 - 54321266
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101751 (version 83.38)
Entrez gene	11201
UniProt	Q9UNA4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UNA4
Antibodypedia	POLI antibodies

PROTEIN BROWSER

POLI-001	POLI-002	POLI-003	POLI-004	POLI-012	POLI-013	POLI-015	POLI-017

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
POLI-001 ENSP00000462664 ENST00000579534	Q9UNA4 [Direct mapping] DNA polymerase iota Show all	Enzymes ENZYME proteins Transferases SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003684 [damaged DNA binding] GO:0003887 [DNA-directed DNA polymerase activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006260 [DNA replication] GO:0006281 [DNA repair] GO:0019985 [translesion synthesis] GO:0042276 [error-prone translesion synthesis] GO:0043231 [intracellular membrane-bounded organelle] GO:0046872 [metal ion binding] GO:0071494 [cellular response to UV-C] Show all	740 aa 83 kDa	No	0
POLI-002 ENSP00000462681 ENST00000579434	J3KSW2 [Direct mapping] DNA polymerase iota Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003684 [damaged DNA binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006281 [DNA repair] GO:0043231 [intracellular membrane-bounded organelle] Show all	637 aa 71.8 kDa	No	0
POLI-003 ENSP00000463071 ENST00000583136	J3KTN3 [Direct mapping] DNA polymerase iota Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006281 [DNA repair] GO:0043231 [intracellular membrane-bounded organelle] Show all	222 aa 24.9 kDa	No	0
POLI-004 ENSP00000464025 ENST00000577612	J3QR36 [Direct mapping] DNA polymerase iota Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006281 [DNA repair] Show all	195 aa 21.4 kDa	No	0
POLI-012 ENSP00000461983 ENST00000580880	J3KRG0 [Direct mapping] DNA polymerase iota Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006281 [DNA repair] Show all	145 aa 16.3 kDa	No	0
POLI-013 ENSP00000463065 ENST00000579823	J3KTM8 [Direct mapping] DNA polymerase iota Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003684 [damaged DNA binding] GO:0006281 [DNA repair] Show all	142 aa 15.9 kDa	No	0
POLI-015 ENSP00000385196 ENST00000406285	J3KQ09 [Direct mapping] DNA polymerase iota Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003684 [damaged DNA binding] GO:0006281 [DNA repair] Show all	661 aa 74.5 kDa	No	0
POLI-017 ENSP00000217800 ENST00000217800	X6R2I3 [Direct mapping] DNA polymerase iota Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003684 [damaged DNA binding] GO:0006281 [DNA repair] Show all	678 aa 76.3 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.