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RIOK3

GENERAL INFORMATION

Gene name

 RIOK3

Gene description

 RIO kinase 3

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in all tissue types.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA001620 , HPA024184
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Gallbladder

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RIOK3 (HGNC Symbol)

Synonyms

 SUDD

Description

 RIO kinase 3 (HGNC Symbol)

Entrez gene summary

 This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]

Chromosome

 18

Cytoband

 q11.2

Chromosome location (bp)

 23452823 - 23486603

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000101782 (version 83.38)

Entrez gene

 8780

UniProt

 O14730 (UniProt - Evidence at protein level)

neXtProt

 NX_O14730

Antibodypedia

 RIOK3 antibodies

PROTEIN BROWSER
RIOK3-001
RIOK3-002
RIOK3-008
RIOK3-011

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RIOK3-001
ENSP00000341874
ENST00000339486
O14730 [Direct mapping]
Serine/threonine-protein kinase RIO3
B0YJ89 [Target identity:100%; Query identity:100%]
RIO kinase 3 (Yeast), isoform CRA_a; Serine/threonine-protein kinase RIO3; cDNA FLJ32730 fis, clone TESTI2001099, highly similar to Serine/threonine-protein kinase RIO3 (EC 2.7.11.1)
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   Atypical kinases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
GO:0007059 [chromosome segregation]
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 519 aa
59.1 kDa 		No 0
RIOK3-002
ENSP00000462548
ENST00000577501
O14730 [Direct mapping]
Serine/threonine-protein kinase RIO3
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   Atypical kinases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
GO:0007059 [chromosome segregation]
Show all
 516 aa
58.7 kDa 		No 0
RIOK3-008
ENSP00000463660
ENST00000581585
B4E1Q4 [Direct mapping]
Serine/threonine-protein kinase RIO3; cDNA FLJ54233, highly similar to Serine/threonine-protein kinase RIO3 (EC 2.7.11.1)
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 503 aa
57.5 kDa 		No 0
RIOK3-011
ENSP00000463644
ENST00000577250
J3QLP4 [Direct mapping]
Serine/threonine-protein kinase RIO3
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 89 aa
9.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.