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Most malignant tissues displayed weak to moderate nuclear staining. Malignant lymphomas, renal and liver cancers were weakly stained or negative.
GENE INFORMATION
Gene name
WDR13
Synonyms
Description
WD repeat domain 13 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is widely expressed in various tissues. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2009]
