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Distinct cytoplasmic staining was found in few adenocarcinomas and malignant carcinoids. Remaining malignant tissues were in general faintly stained or negative.
The protein encoded by this gene belongs to a family of CCCH-type zinc finger proteins that are involved in the proinflammatory activation of macrophages. The exact function of this family member is unknown, but it is thought to function as a ribonuclease. [provided by RefSeq, May 2010]