Cell atlas - CD99L2 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CD99L2
Gene description	CD99 molecule-like 2
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane & the Golgi apparatus. In addition localized to the intermediate filaments.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (uncertain), Plasma membrane (uncertain)
Additional location	In addition localized to the Intermediate filaments (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 2 antibodies. HPA038782 , HPA038783
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane & the Golgi apparatus. In addition localized to the intermediate filaments.

Main location

Golgi apparatus (uncertain), Plasma membrane (uncertain)

Additional location

Intermediate filaments (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA038782	A-431	Golgi apparatus
HPA038782	U-2 OS	Golgi apparatus
HPA038782	U-251 MG	Golgi apparatus
HPA038783	A-431	Plasma membrane
HPA038783	U-2 OS	Plasma membrane
HPA038783	U-2 OS	Intermediate filaments
HPA038783	U-251 MG	Plasma membrane

GENE INFORMATION
Gene name	CD99L2 (HGNC Symbol)
Synonyms	CD99B, MIC2L1
Description	CD99 molecule-like 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Chromosome	X
Cytoband	q28
Chromosome location (bp)	150766337 - 150898816
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000102181 (version 83.38)
Entrez gene	83692
UniProt	Q8TCZ2 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TCZ2
Antibodypedia	CD99L2 antibodies

PROTEIN BROWSER

CD99L2-001	CD99L2-003	CD99L2-005	CD99L2-006	CD99L2-007	CD99L2-201	CD99L2-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD99L2-001 ENSP00000359403 ENST00000370377	Q8TCZ2 [Direct mapping] CD99 antigen-like protein 2 A0A024RC16 [Target identity:100%; Query identity:100%] CD99 antigen-like 2, isoform CRA_d Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0007155 [cell adhesion] GO:0016021 [integral component of membrane] Show all	262 aa 28 kDa	Yes	1
CD99L2-003 ENSP00000391821 ENST00000418547	H0Y4H3 [Direct mapping] CD99 antigen-like protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		157 aa 16.5 kDa	No	0
CD99L2-005 ENSP00000417697 ENST00000466436	Q8TCZ2 [Direct mapping] CD99 antigen-like protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0007155 [cell adhesion] GO:0016021 [integral component of membrane] Show all	213 aa 22.8 kDa	Yes	1
CD99L2-006 ENSP00000489166 ENST00000634795		Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		177 aa 18.7 kDa	No	1
CD99L2-007 ENSP00000347275 ENST00000355149	Q8TCZ2 [Direct mapping] CD99 antigen-like protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0007155 [cell adhesion] GO:0016021 [integral component of membrane] Show all	190 aa 20.3 kDa	Yes	1
CD99L2-201 ENSP00000394858 ENST00000437787	Q8TCZ2 [Direct mapping] CD99 antigen-like protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0007155 [cell adhesion] GO:0016021 [integral component of membrane] Show all	189 aa 20 kDa	Yes	1
CD99L2-202 ENSP00000480322 ENST00000613030	Q8TCZ2 [Direct mapping] CD99 antigen-like protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0007155 [cell adhesion] GO:0016021 [integral component of membrane] Show all	272 aa 28.9 kDa	Yes	1