Cell atlas - VGLL1 - The Human Protein Atlas

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VGLL1

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TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	VGLL1
Gene description	Vestigial-like family member 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus.
RNA cell category	Group enriched (RT4, SK-BR-3, BEWO, A-431, CAPAN-2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA064616
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (RT4, SK-BR-3, BEWO, A-431, CAPAN-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus.

Main location

Nucleus (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA064616	A-431	Nucleus
	HPA064616	RT4	Nucleus
	HPA064616	U-2 OS	Nucleus

GENE INFORMATION
Gene name	VGLL1 (HGNC Symbol)
Synonyms	TDU, TONDU
Description	Vestigial-like family member 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. [provided by RefSeq, Sep 2009]
Chromosome	X
Cytoband	q26.3
Chromosome location (bp)	136532152 - 136556807
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000102243 (version 83.38)
Entrez gene	51442
UniProt	Q99990 (UniProt - Evidence at protein level)
neXtProt	NX_Q99990
Antibodypedia	VGLL1 antibodies

PROTEIN BROWSER

VGLL1-001	VGLL1-002	VGLL1-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
VGLL1-001 ENSP00000359668 ENST00000370634	Q99990 [Direct mapping] Transcription cofactor vestigial-like protein 1 Show all	Predicted intracellular proteins Show all	GO:0003713 [transcription coactivator activity] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008022 [protein C-terminus binding] Show all	258 aa 28.7 kDa	No	0
VGLL1-002 ENSP00000398360 ENST00000440515	H0Y5G3 [Direct mapping] Transcription cofactor vestigial-like protein 1 Show all	Predicted intracellular proteins Show all	GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] Show all	163 aa 17.7 kDa	No	0
VGLL1-004 ENSP00000388868 ENST00000456412	Q5H916 [Direct mapping] Transcription cofactor vestigial-like protein 1 Show all	Predicted intracellular proteins Show all		60 aa 6.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.