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MAPK3

GENERAL INFORMATION

Gene name

 MAPK3

Gene description

 Mitogen-activated protein kinase 3

Protein class

 Cancer-related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

 Intracellular

Number of transcripts

 8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Approved based on 4 antibodies.
HPA003995 , HPA005700 , HPA030069 , CAB002683
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Breast

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 MAPK3 (HGNC Symbol)

Synonyms

 ERK1, p44erk1, p44mapk, PRKM3

Description

 Mitogen-activated protein kinase 3 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 p11.2

Chromosome location (bp)

 30114105 - 30123506

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000102882 (version 83.38)

Entrez gene

 5595

UniProt

 P27361 (UniProt - Evidence at protein level)

neXtProt

 NX_P27361

Antibodypedia

 MAPK3 antibodies

PROTEIN BROWSER
MAPK3-001
MAPK3-003
MAPK3-004
MAPK3-006
MAPK3-007
MAPK3-009
MAPK3-011
MAPK3-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MAPK3-001
ENSP00000263025
ENST00000263025
P27361 [Direct mapping]
Mitogen-activated protein kinase 3
L7RXH5 [Target identity:100%; Query identity:100%]
Mitogen-activated protein kinase
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Cancer-related genes
   Candidate cancer biomarkers
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000187 [activation of MAPK activity]
GO:0000189 [MAPK import into nucleus]
GO:0001784 [phosphotyrosine binding]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0004672 [protein kinase activity]
GO:0004707 [MAP kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005901 [caveola]
GO:0005925 [focal adhesion]
GO:0006351 [transcription, DNA-templated]
GO:0006360 [transcription from RNA polymerase I promoter]
GO:0006361 [transcription initiation from RNA polymerase I promoter]
GO:0006461 [protein complex assembly]
GO:0006468 [protein phosphorylation]
GO:0006915 [apoptotic process]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0006975 [DNA damage induced protein phosphorylation]
GO:0007049 [cell cycle]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0007596 [blood coagulation]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0009636 [response to toxic substance]
GO:0009887 [organ morphogenesis]
GO:0010467 [gene expression]
GO:0014032 [neural crest cell development]
GO:0015630 [microtubule cytoskeleton]
GO:0016032 [viral process]
GO:0016310 [phosphorylation]
GO:0018105 [peptidyl-serine phosphorylation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0019233 [sensory perception of pain]
GO:0019369 [arachidonic acid metabolic process]
GO:0019902 [phosphatase binding]
GO:0030168 [platelet activation]
GO:0030509 [BMP signaling pathway]
GO:0030878 [thyroid gland development]
GO:0031143 [pseudopodium]
GO:0031281 [positive regulation of cyclase activity]
GO:0031663 [lipopolysaccharide-mediated signaling pathway]
GO:0032496 [response to lipopolysaccharide]
GO:0032872 [regulation of stress-activated MAPK cascade]
GO:0033129 [positive regulation of histone phosphorylation]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0034605 [cellular response to heat]
GO:0035066 [positive regulation of histone acetylation]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038083 [peptidyl-tyrosine autophosphorylation]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042473 [outer ear morphogenesis]
GO:0043234 [protein complex]
GO:0043330 [response to exogenous dsRNA]
GO:0045087 [innate immune response]
GO:0045727 [positive regulation of translation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048538 [thymus development]
GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity]
GO:0051216 [cartilage development]
GO:0051403 [stress-activated MAPK cascade]
GO:0051493 [regulation of cytoskeleton organization]
GO:0060020 [Bergmann glial cell differentiation]
GO:0060324 [face development]
GO:0060397 [JAK-STAT cascade involved in growth hormone signaling pathway]
GO:0060425 [lung morphogenesis]
GO:0060440 [trachea formation]
GO:0061308 [cardiac neural crest cell development involved in heart development]
GO:0070062 [extracellular exosome]
GO:0070371 [ERK1 and ERK2 cascade]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070498 [interleukin-1-mediated signaling pathway]
GO:0070849 [response to epidermal growth factor]
GO:0071260 [cellular response to mechanical stimulus]
GO:0072584 [caveolin-mediated endocytosis]
GO:0090170 [regulation of Golgi inheritance]
GO:0097110 [scaffold protein binding]
GO:1900034 [regulation of cellular response to heat]
GO:2000641 [regulation of early endosome to late endosome transport]
GO:2000657 [negative regulation of apolipoprotein binding]
Show all
 379 aa
43.1 kDa 		No 0
MAPK3-003
ENSP00000432742
ENST00000484663
B3KR49 [Direct mapping]
Mitogen-activated protein kinase 3; Mitogen-activated protein kinase 3, isoform CRA_b; cDNA FLJ33690 fis, clone BRAWH2002967, highly similar to Mitogen-activated protein kinase 3 (EC 2.7.11.24)
Show all
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0004672 [protein kinase activity]
GO:0004707 [MAP kinase activity]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0006468 [protein phosphorylation]
GO:0015630 [microtubule cytoskeleton]
Show all
 265 aa
30.6 kDa 		No 0
MAPK3-004
ENSP00000378628
ENST00000395202
P27361 [Direct mapping]
Mitogen-activated protein kinase 3
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Cancer-related genes
   Candidate cancer biomarkers
FDA approved drug targets
   Small molecule drugs
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000187 [activation of MAPK activity]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0004672 [protein kinase activity]
GO:0004707 [MAP kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005901 [caveola]
GO:0005925 [focal adhesion]
GO:0006360 [transcription from RNA polymerase I promoter]
GO:0006361 [transcription initiation from RNA polymerase I promoter]
GO:0006468 [protein phosphorylation]
GO:0006915 [apoptotic process]
GO:0006975 [DNA damage induced protein phosphorylation]
GO:0007049 [cell cycle]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0007596 [blood coagulation]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0015630 [microtubule cytoskeleton]
GO:0016032 [viral process]
GO:0016310 [phosphorylation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0019902 [phosphatase binding]
GO:0030168 [platelet activation]
GO:0030509 [BMP signaling pathway]
GO:0031281 [positive regulation of cyclase activity]
GO:0032872 [regulation of stress-activated MAPK cascade]
GO:0033129 [positive regulation of histone phosphorylation]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0034605 [cellular response to heat]
GO:0035066 [positive regulation of histone acetylation]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038083 [peptidyl-tyrosine autophosphorylation]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity]
GO:0051403 [stress-activated MAPK cascade]
GO:0051493 [regulation of cytoskeleton organization]
GO:0060397 [JAK-STAT cascade involved in growth hormone signaling pathway]
GO:0070062 [extracellular exosome]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070498 [interleukin-1-mediated signaling pathway]
GO:0070849 [response to epidermal growth factor]
GO:0071260 [cellular response to mechanical stimulus]
GO:0072584 [caveolin-mediated endocytosis]
GO:0090170 [regulation of Golgi inheritance]
GO:1900034 [regulation of cellular response to heat]
GO:2000641 [regulation of early endosome to late endosome transport]
Show all
 335 aa
38.3 kDa 		No 0
MAPK3-006
ENSP00000378625
ENST00000395199
P27361 [Direct mapping]
Mitogen-activated protein kinase 3
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Cancer-related genes
   Candidate cancer biomarkers
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000187 [activation of MAPK activity]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0004672 [protein kinase activity]
GO:0004707 [MAP kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005901 [caveola]
GO:0005925 [focal adhesion]
GO:0006360 [transcription from RNA polymerase I promoter]
GO:0006361 [transcription initiation from RNA polymerase I promoter]
GO:0006468 [protein phosphorylation]
GO:0006915 [apoptotic process]
GO:0006975 [DNA damage induced protein phosphorylation]
GO:0007049 [cell cycle]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0007596 [blood coagulation]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0015630 [microtubule cytoskeleton]
GO:0016032 [viral process]
GO:0016310 [phosphorylation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0019902 [phosphatase binding]
GO:0030168 [platelet activation]
GO:0030509 [BMP signaling pathway]
GO:0031281 [positive regulation of cyclase activity]
GO:0032872 [regulation of stress-activated MAPK cascade]
GO:0033129 [positive regulation of histone phosphorylation]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0034605 [cellular response to heat]
GO:0035066 [positive regulation of histone acetylation]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038083 [peptidyl-tyrosine autophosphorylation]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity]
GO:0051403 [stress-activated MAPK cascade]
GO:0051493 [regulation of cytoskeleton organization]
GO:0060397 [JAK-STAT cascade involved in growth hormone signaling pathway]
GO:0070062 [extracellular exosome]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070498 [interleukin-1-mediated signaling pathway]
GO:0070849 [response to epidermal growth factor]
GO:0071260 [cellular response to mechanical stimulus]
GO:0072584 [caveolin-mediated endocytosis]
GO:0090170 [regulation of Golgi inheritance]
GO:1900034 [regulation of cellular response to heat]
GO:2000641 [regulation of early endosome to late endosome transport]
Show all
 357 aa
40.1 kDa 		No 0
MAPK3-007
ENSP00000433639
ENST00000481230
H0YDH9 [Direct mapping]
Mitogen-activated protein kinase 3
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0004672 [protein kinase activity]
GO:0004707 [MAP kinase activity]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0006468 [protein phosphorylation]
Show all
 87 aa
10.2 kDa 		No 0
MAPK3-009
ENSP00000432292
ENST00000478356
E9PRH7 [Direct mapping]
Mitogen-activated protein kinase 3
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0004672 [protein kinase activity]
GO:0004707 [MAP kinase activity]
GO:0005524 [ATP binding]
GO:0005622 [intracellular]
GO:0006468 [protein phosphorylation]
Show all
 136 aa
15.8 kDa 		No 0
MAPK3-011
ENSP00000378626
ENST00000395200
E9PBK7 [Direct mapping]
Mitogen-activated protein kinase 3
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0004672 [protein kinase activity]
GO:0004707 [MAP kinase activity]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0006468 [protein phosphorylation]
GO:0015630 [microtubule cytoskeleton]
Show all
 311 aa
36 kDa 		No 0
MAPK3-201
ENSP00000327293
ENST00000322266
P27361 [Direct mapping]
Mitogen-activated protein kinase 3
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Cancer-related genes
   Candidate cancer biomarkers
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000187 [activation of MAPK activity]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0004672 [protein kinase activity]
GO:0004707 [MAP kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005901 [caveola]
GO:0005925 [focal adhesion]
GO:0006360 [transcription from RNA polymerase I promoter]
GO:0006361 [transcription initiation from RNA polymerase I promoter]
GO:0006468 [protein phosphorylation]
GO:0006915 [apoptotic process]
GO:0006975 [DNA damage induced protein phosphorylation]
GO:0007049 [cell cycle]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0007596 [blood coagulation]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0015630 [microtubule cytoskeleton]
GO:0016032 [viral process]
GO:0016310 [phosphorylation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0019902 [phosphatase binding]
GO:0030168 [platelet activation]
GO:0030509 [BMP signaling pathway]
GO:0031281 [positive regulation of cyclase activity]
GO:0032872 [regulation of stress-activated MAPK cascade]
GO:0033129 [positive regulation of histone phosphorylation]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0034605 [cellular response to heat]
GO:0035066 [positive regulation of histone acetylation]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038083 [peptidyl-tyrosine autophosphorylation]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity]
GO:0051403 [stress-activated MAPK cascade]
GO:0051493 [regulation of cytoskeleton organization]
GO:0060397 [JAK-STAT cascade involved in growth hormone signaling pathway]
GO:0070062 [extracellular exosome]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070498 [interleukin-1-mediated signaling pathway]
GO:0070849 [response to epidermal growth factor]
GO:0071260 [cellular response to mechanical stimulus]
GO:0072584 [caveolin-mediated endocytosis]
GO:0090170 [regulation of Golgi inheritance]
GO:1900034 [regulation of cellular response to heat]
GO:2000641 [regulation of early endosome to late endosome transport]
Show all
 335 aa
38.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.