Expression of NUTF2 in cancer - Summary

CANCER ATLAS

Gene description

Nuclear transport factor 2

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA040915	HPA040956

GENE INFORMATION
Gene name	NUTF2 (HGNC Symbol)
Synonyms	NTF2, PP15
Description	Nuclear transport factor 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a cytosolic factor that facilitates protein transport into the nucleus. It interacts with the nuclear pore complex glycoprotein p62. This encoded protein acts at a relative late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. It is thought to be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import. [provided by RefSeq, Jul 2008]
Chromosome	16
Cytoband	q22.1
Chromosome location (bp)	67846732 - 67872567
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000102898 (version 83.38)
Entrez gene	10204
UniProt	P61970 (UniProt - Evidence at protein level)
neXtProt	NX_P61970
Antibodypedia	NUTF2 antibodies

PROTEIN BROWSER

NUTF2-001	NUTF2-002	NUTF2-003	NUTF2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NUTF2-001 ENSP00000219169 ENST00000219169	P61970 [Direct mapping] Nuclear transport factor 2 A0A024R6Y2 [Target identity:100%; Query identity:100%] Nuclear transport factor 2, isoform CRA_a Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000060 [protein import into nucleus, translocation] GO:0005215 [transporter activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005640 [nuclear outer membrane] GO:0005643 [nuclear pore] GO:0005829 [cytosol] GO:0006611 [protein export from nucleus] GO:0006810 [transport] GO:0008536 [Ran GTPase binding] GO:0042307 [positive regulation of protein import into nucleus] GO:0044613 [nuclear pore central transport channel] GO:0070062 [extracellular exosome] GO:1904046 [negative regulation of vascular endothelial growth factor production] Show all	127 aa 14.5 kDa	No	0
NUTF2-002 ENSP00000456428 ENST00000567105	H3BRV9 [Direct mapping] Nuclear transport factor 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	107 aa 12.2 kDa	No	0
NUTF2-003 ENSP00000457989 ENST00000569436	P61970 [Direct mapping] Nuclear transport factor 2 A0A024R6Y2 [Target identity:100%; Query identity:100%] Nuclear transport factor 2, isoform CRA_a Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000060 [protein import into nucleus, translocation] GO:0005215 [transporter activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005643 [nuclear pore] GO:0005829 [cytosol] GO:0006611 [protein export from nucleus] GO:0006810 [transport] GO:0008536 [Ran GTPase binding] GO:0070062 [extracellular exosome] Show all	127 aa 14.5 kDa	No	0
NUTF2-004 ENSP00000457022 ENST00000568396	P61970 [Direct mapping] Nuclear transport factor 2 A0A024R6Y2 [Target identity:100%; Query identity:100%] Nuclear transport factor 2, isoform CRA_a Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000060 [protein import into nucleus, translocation] GO:0005215 [transporter activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005643 [nuclear pore] GO:0005829 [cytosol] GO:0006611 [protein export from nucleus] GO:0006810 [transport] GO:0008536 [Ran GTPase binding] GO:0070062 [extracellular exosome] Show all	127 aa 14.5 kDa	No	0