Expression of NME3 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

NME/NM23 nucleoside diphosphate kinase 3

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041113

GENE INFORMATION
Gene name	NME3 (HGNC Symbol)
Synonyms	DR-nm23, NDPKC, NM23-H3
Description	NME/NM23 nucleoside diphosphate kinase 3 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	1770286 - 1771730
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000103024 (version 83.38)
Entrez gene	4832
UniProt	Q13232 (UniProt - Evidence at protein level)
neXtProt	NX_Q13232
Antibodypedia	NME3 antibodies

PROTEIN BROWSER

NME3-001	NME3-003	NME3-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NME3-001 ENSP00000219302 ENST00000219302	Q13232 [Direct mapping] Nucleoside diphosphate kinase 3 Show all	Enzymes ENZYME proteins Transferases Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004550 [nucleoside diphosphate kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005622 [intracellular] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0006163 [purine nucleotide metabolic process] GO:0006165 [nucleoside diphosphate phosphorylation] GO:0006183 [GTP biosynthetic process] GO:0006220 [pyrimidine nucleotide metabolic process] GO:0006228 [UTP biosynthetic process] GO:0006241 [CTP biosynthetic process] GO:0006915 [apoptotic process] GO:0009142 [nucleoside triphosphate biosynthetic process] GO:0042981 [regulation of apoptotic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	169 aa 19 kDa	Yes	0
NME3-003 ENSP00000455435 ENST00000563498	H3BPR2 [Direct mapping] Nucleoside diphosphate kinase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004550 [nucleoside diphosphate kinase activity] GO:0005524 [ATP binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0006163 [purine nucleotide metabolic process] GO:0006165 [nucleoside diphosphate phosphorylation] GO:0006183 [GTP biosynthetic process] GO:0006220 [pyrimidine nucleotide metabolic process] GO:0006228 [UTP biosynthetic process] GO:0006241 [CTP biosynthetic process] GO:0009142 [nucleoside triphosphate biosynthetic process] GO:0042981 [regulation of apoptotic process] Show all	85 aa 9.3 kDa	No	0
NME3-009 ENSP00000456160 ENST00000564628	H3BRA8 [Direct mapping] Nucleoside diphosphate kinase 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004550 [nucleoside diphosphate kinase activity] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0006163 [purine nucleotide metabolic process] GO:0006165 [nucleoside diphosphate phosphorylation] GO:0006183 [GTP biosynthetic process] GO:0006220 [pyrimidine nucleotide metabolic process] GO:0006228 [UTP biosynthetic process] GO:0006241 [CTP biosynthetic process] GO:0009142 [nucleoside triphosphate biosynthetic process] GO:0042981 [regulation of apoptotic process] Show all	123 aa 13.5 kDa	No	0