Expression of NPRL3 in cancer - Summary

CANCER ATLAS

Gene description

NPR3-like, GATOR1 complex subunit

Protein class

Disease related genes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA011741

GENE INFORMATION
Gene name	NPRL3 (HGNC Symbol)
Synonyms	C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11
Description	NPR3-like, GATOR1 complex subunit (HGNC Symbol)
Entrez gene summary	The function of the encoded protein is not known. [provided by RefSeq, Aug 2011]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	84271 - 138860
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000103148 (version 83.38)
Entrez gene	8131
UniProt	Q12980 (UniProt - Evidence at protein level)
neXtProt	NX_Q12980
Antibodypedia	NPRL3 antibodies

PROTEIN BROWSER

NPRL3-003	NPRL3-010	NPRL3-011	NPRL3-015	NPRL3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NPRL3-003 ENSP00000382834 ENST00000399953	B7Z6Q0 [Direct mapping] Nitrogen permease regulator 3-like protein; cDNA FLJ53204, highly similar to CGTHBA protein Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		544 aa 60.8 kDa	No	0
NPRL3-010 ENSP00000477764 ENST00000468260	A0A087WTD0 [Direct mapping] Nitrogen permease regulator 3-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		202 aa 22.6 kDa	No	0
NPRL3-011 ENSP00000399894 ENST00000419636	B1B1F5 [Direct mapping] Chromosome 16 open reading frame 35; Nitrogen permease regulator 3-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		182 aa 20.2 kDa	No	0
NPRL3-015 ENSP00000478273 ENST00000611875	Q12980 [Direct mapping] Nitrogen permease regulator 3-like protein Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005096 [GTPase activator activity] GO:0005575 [cellular_component] GO:0008150 [biological_process] GO:0032007 [negative regulation of TOR signaling] GO:0034198 [cellular response to amino acid starvation] GO:0043547 [positive regulation of GTPase activity] GO:1990130 [Iml1 complex] Show all	569 aa 63.6 kDa	No	0
NPRL3-201 ENSP00000483814 ENST00000620134	Q12980 [Direct mapping] Nitrogen permease regulator 3-like protein Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0003281 [ventricular septum development] GO:0003674 [molecular_function] GO:0005096 [GTPase activator activity] GO:0005575 [cellular_component] GO:0008150 [biological_process] GO:0032007 [negative regulation of TOR signaling] GO:0034198 [cellular response to amino acid starvation] GO:0035909 [aorta morphogenesis] GO:0043547 [positive regulation of GTPase activity] GO:0048738 [cardiac muscle tissue development] GO:0060021 [palate development] GO:1990130 [Iml1 complex] Show all	569 aa 63.6 kDa	No	0