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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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SLC7A5
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

SLC7A5

Gene description

Solute carrier family 7 (amino acid transporter light chain, L system), member 5

Protein class

Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (cerebral cortex, testis)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data.

Reliability score

Approved based on 1 antibody.
HPA052673
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex, testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

SLC7A5 (HGNC Symbol)

Synonyms

CD98, D16S469E, E16, LAT1, MPE16

Description

Solute carrier family 7 (amino acid transporter light chain, L system), member 5 (HGNC Symbol)

Entrez gene summary

Chromosome

16

Cytoband

q24.2

Chromosome location (bp)

87830023 - 87869488

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103257 (version 83.38)

Entrez gene

8140

UniProt

Q01650 (UniProt - Evidence at protein level)

neXtProt

NX_Q01650

Antibodypedia

SLC7A5 antibodies

PROTEIN BROWSER

SLC7A5-001
SLC7A5-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC7A5-001
ENSP00000261622
ENST00000261622
Q01650 [Direct mapping]
Large neutral amino acids transporter small subunit 1
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003333 [amino acid transmembrane transport]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006520 [cellular amino acid metabolic process]
GO:0006810 [transport]
GO:0006811 [ion transport]
GO:0006865 [amino acid transport]
GO:0007399 [nervous system development]
GO:0007596 [blood coagulation]
GO:0015171 [amino acid transmembrane transporter activity]
GO:0015175 [neutral amino acid transmembrane transporter activity]
GO:0015179 [L-amino acid transmembrane transporter activity]
GO:0015190 [L-leucine transmembrane transporter activity]
GO:0015192 [L-phenylalanine transmembrane transporter activity]
GO:0015196 [L-tryptophan transmembrane transporter activity]
GO:0015297 [antiporter activity]
GO:0015804 [neutral amino acid transport]
GO:0015807 [L-amino acid transport]
GO:0015820 [leucine transport]
GO:0015823 [phenylalanine transport]
GO:0015827 [tryptophan transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016324 [apical plasma membrane]
GO:0030154 [cell differentiation]
GO:0042605 [peptide antigen binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0050900 [leukocyte migration]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0098655 [cation transmembrane transport]
GO:1902475 [L-alpha-amino acid transmembrane transport]
Show all
507 aa
55 kDa
No >9
SLC7A5-002
ENSP00000454323
ENST00000565644
A0A0C4DGL4 [Direct mapping]
Large neutral amino acids transporter small subunit 1; Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 5, isoform CRA_b
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003333 [amino acid transmembrane transport]
GO:0005887 [integral component of plasma membrane]
GO:0015171 [amino acid transmembrane transporter activity]
GO:0015190 [L-leucine transmembrane transporter activity]
GO:0015192 [L-phenylalanine transmembrane transporter activity]
GO:0015196 [L-tryptophan transmembrane transporter activity]
GO:0015297 [antiporter activity]
GO:0015807 [L-amino acid transport]
GO:0015820 [leucine transport]
GO:0015823 [phenylalanine transport]
GO:0015827 [tryptophan transport]
GO:0016020 [membrane]
GO:0098655 [cation transmembrane transport]
GO:1902475 [L-alpha-amino acid transmembrane transport]
Show all
241 aa
27.2 kDa
No 6

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