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METRN

GENERAL INFORMATION

Gene name

 METRN

Gene description

 Meteorin, glial cell differentiation regulator

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Reliability score

 Approved based on 1 antibody.
HPA051164
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 METRN (HGNC Symbol)

Synonyms

 C16orf23, MGC2601

Description

 Meteorin, glial cell differentiation regulator (HGNC Symbol)

Entrez gene summary

 Meteorin regulates glial cell differentiation and promotes the formation of axonal networks during neurogenesis (Nishino et al., 2004 [PubMed 15085178]).[supplied by OMIM, Mar 2008]

Chromosome

 16

Cytoband

 p13.3

Chromosome location (bp)

 715115 - 719655

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000103260 (version 83.38)

Entrez gene

 79006

UniProt

 Q9UJH8 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9UJH8

Antibodypedia

 METRN antibodies

PROTEIN BROWSER
METRN-001
METRN-004
METRN-005
METRN-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
METRN-001
ENSP00000455068
ENST00000568223
Q9UJH8 [Direct mapping]
Meteorin
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0010001 [glial cell differentiation]
GO:0050772 [positive regulation of axonogenesis]
Show all
 293 aa
31.2 kDa 		Yes 0
METRN-004
ENSP00000219542
ENST00000219542
J3KMW6 [Direct mapping]
Meteorin
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 187 aa
19.7 kDa 		No 0
METRN-005
ENSP00000459900
ENST00000567076
I3L2T3 [Direct mapping]
Meteorin
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 175 aa
18.5 kDa 		No 0
METRN-006
ENSP00000457702
ENST00000568415
H3BUM1 [Direct mapping]
Meteorin
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 160 aa
17.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.