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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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MAZ
  • TISSUE

  • premium

    CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

MYC-associated zinc finger protein (purine-binding transcription factor)

Protein class

Predicted intracellular proteins, Predicted secreted proteins, Transcription factors

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA048315

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Cancer tissues displayed weak to moderate cytoplasmic and/or nuclear staining. Occasional cases of melanomas, thyroid, breast and urothelial cancers were strongly stained. Several cases of stomach, endometrial and colorectal cancers were negative.

GENE INFORMATION

Gene name

MAZ (HGNC Symbol)

Synonyms

Pur-1, ZF87, Zif87, ZNF801

Description

MYC-associated zinc finger protein (purine-binding transcription factor) (HGNC Symbol)

Entrez gene summary

Chromosome

16

Cytoband

p11.2

Chromosome location (bp)

29806106 - 29811164

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103495 (version 83.38)

Entrez gene

4150

UniProt

P56270 (UniProt - Evidence at protein level)

neXtProt

NX_P56270

Antibodypedia

MAZ antibodies

PROTEIN BROWSER

«
MAZ-001
MAZ-002
MAZ-003
MAZ-004
MAZ-005
MAZ-008
MAZ-009
MAZ-014
MAZ-015
MAZ-016
MAZ-017
MAZ-018
MAZ-022
MAZ-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAZ-001
ENSP00000313362
ENST00000322945
P56270 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000979 [RNA polymerase II core promoter sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006369 [termination of RNA polymerase II transcription]
GO:0044822 [poly(A) RNA binding]
GO:0046872 [metal ion binding]
Show all
477 aa
48.6 kDa
Yes 0
MAZ-002
ENSP00000455726
ENST00000562337
P56270 [Direct mapping]
Myc-associated zinc finger protein
Show all
   SCAMPI predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000979 [RNA polymerase II core promoter sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006369 [termination of RNA polymerase II transcription]
GO:0044822 [poly(A) RNA binding]
GO:0046872 [metal ion binding]
Show all
172 aa
17.8 kDa
Yes 0
MAZ-003
ENSP00000461174
ENST00000566906
I3L4D3 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
184 aa
19.3 kDa
Yes 0
MAZ-004
ENSP00000219782
ENST00000219782
P56270 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000979 [RNA polymerase II core promoter sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006369 [termination of RNA polymerase II transcription]
GO:0044822 [poly(A) RNA binding]
GO:0046872 [metal ion binding]
Show all
493 aa
51.1 kDa
Yes 0
MAZ-005
ENSP00000443956
ENST00000545521
P56270 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000979 [RNA polymerase II core promoter sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006369 [termination of RNA polymerase II transcription]
GO:0044822 [poly(A) RNA binding]
GO:0046872 [metal ion binding]
Show all
454 aa
46.4 kDa
No 0
MAZ-008
ENSP00000455473
ENST00000568544
H3BPU3 [Direct mapping]
MYC-associated zinc finger protein (Purine-binding transcription factor), isoform CRA_a; Myc-associated zinc finger protein
Show all
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
78 aa
7.6 kDa
No 0
MAZ-009
ENSP00000458201
ENST00000568282
I3L0M3 [Direct mapping]
MYC-associated zinc finger protein (Purine-binding transcription factor), isoform CRA_e; Myc-associated zinc finger protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0046872 [metal ion binding]
Show all
94 aa
10.1 kDa
No 0
MAZ-014
ENSP00000455794
ENST00000568411
H3BQI4 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0046872 [metal ion binding]
Show all
196 aa
20.6 kDa
No 0
MAZ-015
ENSP00000460057
ENST00000567444
I3L2Z5 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0046872 [metal ion binding]
Show all
202 aa
22.2 kDa
No 0
MAZ-016
ENSP00000460877
ENST00000569978
I3L411 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
53 aa
5.5 kDa
No 0
MAZ-017
ENSP00000455913
ENST00000563012
H3BQS2 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0046872 [metal ion binding]
Show all
152 aa
16 kDa
No 0
MAZ-018
ENSP00000461630
ENST00000562557
I3L4Y2 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0046872 [metal ion binding]
Show all
79 aa
8.6 kDa
No 0
MAZ-022
ENSP00000457310
ENST00000563402
H3BTS8 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
186 aa
19.4 kDa
Yes 0
MAZ-201
ENSP00000480440
ENST00000616501
A0A087WWR2 [Direct mapping]
Myc-associated zinc finger protein
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0046872 [metal ion binding]
Show all
252 aa
26.8 kDa
Yes 0

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