Expression of ZDHHC2 in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger, DHHC-type containing 2

Protein class

Enzymes, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA023331

GENE INFORMATION
Gene name	ZDHHC2 (HGNC Symbol)
Synonyms	ZNF372
Description	Zinc finger, DHHC-type containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	p22
Chromosome location (bp)	17156029 - 17224799
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000104219 (version 83.38)
Entrez gene	51201
UniProt	Q9UIJ5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9UIJ5
Antibodypedia	ZDHHC2 antibodies

PROTEIN BROWSER

ZDHHC2-001	ZDHHC2-002	ZDHHC2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZDHHC2-001 ENSP00000262096 ENST00000262096	Q9UIJ5 [Direct mapping] Palmitoyltransferase ZDHHC2 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006612 [protein targeting to membrane] GO:0008270 [zinc ion binding] GO:0016409 [palmitoyltransferase activity] GO:0018230 [peptidyl-L-cysteine S-palmitoylation] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] GO:0044267 [cellular protein metabolic process] GO:0055038 [recycling endosome membrane] Show all	367 aa 42 kDa	No	4
ZDHHC2-002 ENSP00000430804 ENST00000523132		Predicted intracellular proteins Show all		7 aa 0.8 kDa	No	0
ZDHHC2-003 ENSP00000430317 ENST00000522184	E5RFZ7 [Direct mapping] Palmitoyltransferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	130 aa 15.4 kDa	No	1