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TRIM35

GENERAL INFORMATION

Gene name

 TRIM35

Gene description

 Tripartite motif containing 35

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous nuclear and cytoplasmic expression in

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA019647
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 TRIM35 (HGNC Symbol)

Synonyms

 HLS5, KIAA1098, MAIR

Description

 Tripartite motif containing 35 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008]

Chromosome

 8

Cytoband

 p21.2

Chromosome location (bp)

 27284887 - 27311319

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000104228 (version 83.38)

Entrez gene

 23087

UniProt

 Q9UPQ4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UPQ4

Antibodypedia

 TRIM35 antibodies

PROTEIN BROWSER
TRIM35-001
TRIM35-003
TRIM35-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRIM35-001
ENSP00000301924
ENST00000305364
Q9UPQ4 [Direct mapping]
Tripartite motif-containing protein 35
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006915 [apoptotic process]
GO:0008270 [zinc ion binding]
GO:0043065 [positive regulation of apoptotic process]
GO:0045087 [innate immune response]
GO:0045930 [negative regulation of mitotic cell cycle]
GO:1902187 [negative regulation of viral release from host cell]
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 493 aa
56.5 kDa 		No 0
TRIM35-003
ENSP00000428770
ENST00000521253
E5RGB3 [Direct mapping]
Tripartite motif-containing protein 35
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
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 266 aa
30.6 kDa 		No 0
TRIM35-004
ENSP00000429356
ENST00000521283
H0YBF3 [Direct mapping]
Tripartite motif-containing protein 35
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 100 aa
11.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.