Tissue expression of FGL1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	FGL1
Gene description	Fibrinogen-like 1
Protein class	Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (liver)
GTEx:	Tissue enriched (liver)
FANTOM5:	Tissue enriched (liver)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (liver)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (liver)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (liver)

GENE INFORMATION
Gene name	FGL1 (HGNC Symbol)
Synonyms	HFREP-1
Description	Fibrinogen-like 1 (HGNC Symbol)
Entrez gene summary	Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]
Chromosome	8
Cytoband	p22
Chromosome location (bp)	17864380 - 17910365
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000104760 (version 83.38)
Entrez gene	2267
UniProt	Q08830 (UniProt - Evidence at protein level)
neXtProt	NX_Q08830
Antibodypedia	FGL1 antibodies

PROTEIN BROWSER

FGL1-002	FGL1-004	FGL1-008	FGL1-201	FGL1-202	FGL1-203	FGL1-204

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FGL1-002 ENSP00000381133 ENST00000398056	Q08830 [Direct mapping] Fibrinogen-like protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005577 [fibrinogen complex] GO:0070062 [extracellular exosome] Show all	312 aa 36.4 kDa	Yes	0
FGL1-004 ENSP00000429757 ENST00000522444	Q08830 [Direct mapping] Fibrinogen-like protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005577 [fibrinogen complex] GO:0070062 [extracellular exosome] Show all	312 aa 36.4 kDa	Yes	0
FGL1-008 ENSP00000428430 ENST00000518650	Q08830 [Direct mapping] Fibrinogen-like protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005577 [fibrinogen complex] GO:0070062 [extracellular exosome] Show all	312 aa 36.4 kDa	Yes	0
FGL1-201 ENSP00000371262 ENST00000381840	Q08830 [Direct mapping] Fibrinogen-like protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005577 [fibrinogen complex] GO:0070062 [extracellular exosome] Show all	312 aa 36.4 kDa	Yes	0
FGL1-202 ENSP00000371263 ENST00000381841	Q08830 [Direct mapping] Fibrinogen-like protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005577 [fibrinogen complex] GO:0070062 [extracellular exosome] Show all	312 aa 36.4 kDa	Yes	0
FGL1-203 ENSP00000381131 ENST00000398054	Q08830 [Direct mapping] Fibrinogen-like protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005577 [fibrinogen complex] GO:0070062 [extracellular exosome] Show all	312 aa 36.4 kDa	Yes	0
FGL1-204 ENSP00000401952 ENST00000427924	Q08830 [Direct mapping] Fibrinogen-like protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005577 [fibrinogen complex] GO:0070062 [extracellular exosome] Show all	312 aa 36.4 kDa	Yes	0