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RELB

CANCER ATLAS

Gene description

 V-rel avian reticuloendotheliosis viral oncogene homolog B

Protein class

 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Lymphoma

STAINING SUMMARY
HPA040506
CAB007753

GENE INFORMATION

Gene name

 RELB (HGNC Symbol)

Synonyms

 REL-B

Description

 V-rel avian reticuloendotheliosis viral oncogene homolog B (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 q13.32

Chromosome location (bp)

 45001430 - 45038198

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000104856 (version 83.38)

Entrez gene

 5971

UniProt

 Q01201 (UniProt - Evidence at protein level)

neXtProt

 NX_Q01201

Antibodypedia

 RELB antibodies

PROTEIN BROWSER
RELB-001
RELB-002
RELB-006
RELB-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RELB-001
ENSP00000221452
ENST00000221452
Q01201 [Direct mapping]
Transcription factor RelB
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Immunoglobulin fold
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001047 [core promoter binding]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006954 [inflammatory response]
GO:0007249 [I-kappaB kinase/NF-kappaB signaling]
GO:0010628 [positive regulation of gene expression]
GO:0019882 [antigen processing and presentation]
GO:0032688 [negative regulation of interferon-beta production]
GO:0032922 [circadian regulation of gene expression]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0033256 [I-kappaB/NF-kappaB complex]
GO:0034097 [response to cytokine]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0042088 [T-helper 1 type immune response]
GO:0043011 [myeloid dendritic cell differentiation]
GO:0045063 [T-helper 1 cell differentiation]
GO:0045087 [innate immune response]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0071470 [cellular response to osmotic stress]
Show all
 579 aa
62.1 kDa 		No 0
RELB-002
ENSP00000423287
ENST00000505236
D6R992 [Direct mapping]
Transcription factor RelB; V-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (Avian)
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006954 [inflammatory response]
GO:0007249 [I-kappaB kinase/NF-kappaB signaling]
GO:0033256 [I-kappaB/NF-kappaB complex]
GO:0034097 [response to cytokine]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
Show all
 576 aa
61.8 kDa 		No 0
RELB-006
ENSP00000468460
ENST00000589972
K7ERX9 [Direct mapping]
Transcription factor RelB
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003682 [chromatin binding]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0006954 [inflammatory response]
GO:0007249 [I-kappaB kinase/NF-kappaB signaling]
GO:0033256 [I-kappaB/NF-kappaB complex]
GO:0034097 [response to cytokine]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
Show all
 142 aa
14.2 kDa 		No 0
RELB-201
ENSP00000485826
ENST00000625761
Q01201 [Direct mapping]
Transcription factor RelB
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Immunoglobulin fold
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001047 [core promoter binding]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006954 [inflammatory response]
GO:0007249 [I-kappaB kinase/NF-kappaB signaling]
GO:0032688 [negative regulation of interferon-beta production]
GO:0032922 [circadian regulation of gene expression]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0033256 [I-kappaB/NF-kappaB complex]
GO:0034097 [response to cytokine]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
Show all
 579 aa
62.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.