Cell atlas - CKM - The Human Protein Atlas

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CKM

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CKM
Gene description	Creatine kinase, muscle
Protein class	Candidate cardiovascular disease genes Enzymes FDA approved drug targets Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (SCLC-21H)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (SCLC-21H) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CKM (HGNC Symbol)
Synonyms	CKMM
Description	Creatine kinase, muscle (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	q13.32
Chromosome location (bp)	45306414 - 45322977
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000104879 (version 83.38)
Entrez gene	1158
UniProt	P06732 (UniProt - Evidence at protein level)
neXtProt	NX_P06732
Antibodypedia	CKM antibodies

PROTEIN BROWSER

CKM-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CKM-001 ENSP00000221476 ENST00000221476	P06732 [Direct mapping] Creatine kinase M-type Creatine kinase M-type, N-terminally processed Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Plasma proteins Candidate cardiovascular disease genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004111 [creatine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005829 [cytosol] GO:0006595 [polyamine metabolic process] GO:0006600 [creatine metabolic process] GO:0016301 [kinase activity] GO:0016310 [phosphorylation] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0034641 [cellular nitrogen compound metabolic process] GO:0044281 [small molecule metabolic process] GO:0046314 [phosphocreatine biosynthetic process] Show all	381 aa 43.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.