Expression of TRMT1 in cancer - Summary

CANCER ATLAS

Gene description

TRNA methyltransferase 1

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Stomach cancer

STAINING SUMMARY

HPA041130	HPA041380

GENE INFORMATION
Gene name	TRMT1 (HGNC Symbol)
Synonyms	FLJ20244, TRM1
Description	TRNA methyltransferase 1 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.13
Chromosome location (bp)	13104902 - 13117567
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000104907 (version 83.38)
Entrez gene	55621
UniProt	Q9NXH9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NXH9
Antibodypedia	TRMT1 antibodies

PROTEIN BROWSER

TRMT1-001	TRMT1-002	TRMT1-012	TRMT1-019	TRMT1-020	TRMT1-201	TRMT1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRMT1-001 ENSP00000466967 ENST00000592062	Q9NXH9 [Direct mapping] tRNA (guanine(26)-N(2))-dimethyltransferase A0A024R7I5 [Target identity:100%; Query identity:100%] TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae), isoform CRA_c Show all	Enzymes ENZYME proteins Transferases THUMBUP predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000049 [tRNA binding] GO:0002940 [tRNA N2-guanine methylation] GO:0003723 [RNA binding] GO:0004809 [tRNA (guanine-N2-)-methyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0006400 [tRNA modification] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0044822 [poly(A) RNA binding] GO:0046872 [metal ion binding] Show all	659 aa 72.2 kDa	No	0
TRMT1-002 ENSP00000221504 ENST00000221504	Q9NXH9 [Direct mapping] tRNA (guanine(26)-N(2))-dimethyltransferase Show all	Enzymes ENZYME proteins Transferases THUMBUP predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000049 [tRNA binding] GO:0002940 [tRNA N2-guanine methylation] GO:0003723 [RNA binding] GO:0004809 [tRNA (guanine-N2-)-methyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0006400 [tRNA modification] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0044822 [poly(A) RNA binding] GO:0046872 [metal ion binding] Show all	630 aa 69.3 kDa	No	0
TRMT1-012 ENSP00000465370 ENST00000587487	K7EJX9 [Direct mapping] tRNA (guanine(26)-N(2))-dimethyltransferase Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002940 [tRNA N2-guanine methylation] GO:0003723 [RNA binding] GO:0004809 [tRNA (guanine-N2-)-methyltransferase activity] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0008033 [tRNA processing] Show all	191 aa 20.7 kDa	No	0
TRMT1-019 ENSP00000467938 ENST00000592814	K7EQQ8 [Direct mapping] tRNA (guanine(26)-N(2))-dimethyltransferase Show all	THUMBUP predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002940 [tRNA N2-guanine methylation] GO:0003723 [RNA binding] GO:0004809 [tRNA (guanine-N2-)-methyltransferase activity] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0008033 [tRNA processing] Show all	297 aa 32.8 kDa	No	0
TRMT1-020 ENSP00000467984 ENST00000588229	K7EQU7 [Direct mapping] tRNA (guanine(26)-N(2))-dimethyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002940 [tRNA N2-guanine methylation] GO:0003723 [RNA binding] GO:0004809 [tRNA (guanine-N2-)-methyltransferase activity] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0008033 [tRNA processing] Show all	145 aa 15.8 kDa	No	0
TRMT1-201 ENSP00000350352 ENST00000357720	Q9NXH9 [Direct mapping] tRNA (guanine(26)-N(2))-dimethyltransferase A0A024R7I5 [Target identity:100%; Query identity:100%] TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae), isoform CRA_c Show all	Enzymes ENZYME proteins Transferases THUMBUP predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000049 [tRNA binding] GO:0002940 [tRNA N2-guanine methylation] GO:0003723 [RNA binding] GO:0004809 [tRNA (guanine-N2-)-methyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0006400 [tRNA modification] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0044822 [poly(A) RNA binding] GO:0046872 [metal ion binding] Show all	659 aa 72.2 kDa	No	0
TRMT1-202 ENSP00000416149 ENST00000437766	Q9NXH9 [Direct mapping] tRNA (guanine(26)-N(2))-dimethyltransferase A0A024R7I5 [Target identity:100%; Query identity:100%] TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae), isoform CRA_c Show all	Enzymes ENZYME proteins Transferases THUMBUP predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000049 [tRNA binding] GO:0002940 [tRNA N2-guanine methylation] GO:0003723 [RNA binding] GO:0004809 [tRNA (guanine-N2-)-methyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0006400 [tRNA modification] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0044822 [poly(A) RNA binding] GO:0046872 [metal ion binding] Show all	659 aa 72.2 kDa	No	0