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STX10

GENERAL INFORMATION

Gene name

 STX10

Gene description

 Syntaxin 10

Protein class

 Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression with a few cases of nuclear expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA035303
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 STX10 (HGNC Symbol)

Synonyms

 hsyn10, SYN10

Description

 Syntaxin 10 (HGNC Symbol)

Entrez gene summary

 This gene belongs to the syntaxin family and encodes a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE). The encoded protein is involved in docking and fusion events at the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]

Chromosome

 19

Cytoband

 p13.13

Chromosome location (bp)

 13144058 - 13150383

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000104915 (version 83.38)

Entrez gene

 8677

UniProt

 O60499 (UniProt - Evidence at protein level)

neXtProt

 NX_O60499

Antibodypedia

 STX10 antibodies

PROTEIN BROWSER
STX10-002
STX10-003
STX10-004
STX10-005
STX10-006
STX10-007
STX10-008
STX10-009
STX10-011

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STX10-002
ENSP00000466298
ENST00000587230
O60499 [Direct mapping]
Syntaxin-10
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0005802 [trans-Golgi network]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0019905 [syntaxin binding]
GO:0031201 [SNARE complex]
GO:0031982 [vesicle]
GO:0032880 [regulation of protein localization]
GO:0042147 [retrograde transport, endosome to Golgi]
GO:0048193 [Golgi vesicle transport]
GO:0048471 [perinuclear region of cytoplasm]
Show all
 249 aa
28.1 kDa 		No 1
STX10-003
ENSP00000339350
ENST00000343587
O60499 [Direct mapping]
Syntaxin-10
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0005802 [trans-Golgi network]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0019905 [syntaxin binding]
GO:0031201 [SNARE complex]
GO:0031982 [vesicle]
GO:0032880 [regulation of protein localization]
GO:0042147 [retrograde transport, endosome to Golgi]
GO:0048193 [Golgi vesicle transport]
GO:0048471 [perinuclear region of cytoplasm]
Show all
 200 aa
22.4 kDa 		No 1
STX10-004
ENSP00000242770
ENST00000242770
X6R2W0 [Direct mapping]
Syntaxin-10
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0031201 [SNARE complex]
GO:0048193 [Golgi vesicle transport]
Show all
 220 aa
24.9 kDa 		No 0
STX10-005
ENSP00000465398
ENST00000589083
Q5U8S2 [Direct mapping]
Syntaxin 10; Syntaxin-10
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0031201 [SNARE complex]
GO:0048193 [Golgi vesicle transport]
Show all
 246 aa
27.6 kDa 		No 0
STX10-006
ENSP00000464970
ENST00000591197
K7EJ05 [Direct mapping]
Syntaxin-10
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005484 [SNAP receptor activity]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0016021 [integral component of membrane]
GO:0031201 [SNARE complex]
Show all
 58 aa
6.4 kDa 		No 0
STX10-007
ENSP00000466272
ENST00000593126
K7ELY2 [Direct mapping]
Syntaxin-10
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0031201 [SNARE complex]
GO:0048193 [Golgi vesicle transport]
Show all
 201 aa
22.5 kDa 		No 0
STX10-008
ENSP00000464943
ENST00000587318
K7EIY4 [Direct mapping]
Syntaxin-10
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0031201 [SNARE complex]
GO:0048193 [Golgi vesicle transport]
Show all
 228 aa
25.5 kDa 		No 0
STX10-009
ENSP00000467713
ENST00000591415
K7EQ84 [Direct mapping]
Syntaxin-10
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0031201 [SNARE complex]
Show all
 98 aa
10.6 kDa 		No 0
STX10-011
ENSP00000467479
ENST00000588848
K7EPP9 [Direct mapping]
Syntaxin-10
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0031201 [SNARE complex]
Show all
 122 aa
13.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.