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Cancer tissues displayed weak to moderate nuclear staining with additional cytoplasmic and/or membranous positivity in few tissues. Few cases of malignant gliomas, malignant melanomas, colorectal, breast, cervical, urothelial and renal cancers were strongly stained. Several cases of malignant lymphomas and liver cancers were negative.
GENE INFORMATION
Gene name
SGTA (HGNC Symbol)
Synonyms
SGT
Description
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha (HGNC Symbol)
Entrez gene summary
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function. [provided by RefSeq, Jul 2008]