Cell atlas - ILVBL - The Human Protein Atlas

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ILVBL

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus
	Vesicles

Human cell
	Golgi Apparatus
	Vesicles

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GENERAL INFORMATION
Gene name	ILVBL
Gene description	IlvB (bacterial acetolactate synthase)-like
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the Golgi apparatus & vesicles.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (approved), Vesicles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA067682
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the Golgi apparatus & vesicles.

Main location

Golgi apparatus (approved), Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA067682	MCF7	Golgi apparatus
	HPA067682	MCF7	Vesicles
	HPA067682	U-2 OS	Golgi apparatus
	HPA067682	U-2 OS	Vesicles

GENE INFORMATION
Gene name	ILVBL (HGNC Symbol)
Synonyms	209L8, AHAS, FLJ39061, ILV2H, MGC1269, MGC19535
Description	IlvB (bacterial acetolactate synthase)-like (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene shares similarity with several thiamine pyrophosphate-binding proteins identified in bacteria, yeast, and plants. The highest degree of similarity is found with bacterial acetolactate synthases (AHAS), which are enzymes that catalyze the first step in branched-chain amino acid biosynthesis. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.12
Chromosome location (bp)	15114984 - 15125785
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105135 (version 83.38)
Entrez gene	10994
UniProt	A1L0T0 (UniProt - Evidence at protein level)
neXtProt	NX_A1L0T0
Antibodypedia	ILVBL antibodies

PROTEIN BROWSER

ILVBL-001	ILVBL-002	ILVBL-006	ILVBL-008	ILVBL-013	ILVBL-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ILVBL-001 ENSP00000263383 ENST00000263383	A1L0T0 [Direct mapping] Acetolactate synthase-like protein Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0003674 [molecular_function] GO:0003824 [catalytic activity] GO:0005515 [protein binding] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016740 [transferase activity] GO:0030976 [thiamine pyrophosphate binding] Show all	632 aa 67.9 kDa	No	0
ILVBL-002 ENSP00000470942 ENST00000534378	M0R026 [Direct mapping] Acetolactate synthase-like protein Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0003824 [catalytic activity] GO:0008152 [metabolic process] GO:0030976 [thiamine pyrophosphate binding] Show all	525 aa 56.7 kDa	No	0
ILVBL-006 ENSP00000433355 ENST00000533747	E9PL44 [Direct mapping] Acetolactate synthase-like protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0030976 [thiamine pyrophosphate binding] Show all	166 aa 16.9 kDa	No	1
ILVBL-008 ENSP00000435516 ENST00000527093	E9PJS0 [Direct mapping] Acetolactate synthase-like protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0030976 [thiamine pyrophosphate binding] Show all	262 aa 27.6 kDa	No	1
ILVBL-013 ENSP00000471762 ENST00000600984	M0R1B5 [Direct mapping] Acetolactate synthase-like protein Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0030976 [thiamine pyrophosphate binding] Show all	166 aa 17.6 kDa	No	0
ILVBL-015 ENSP00000470834 ENST00000598709	M0QZX5 [Direct mapping] Acetolactate synthase-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0030976 [thiamine pyrophosphate binding] Show all	230 aa 25.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.