Expression of SYDE1 in cancer - Summary

CANCER ATLAS

Gene description

Synapse defective 1, Rho GTPase, homolog 1 (C. elegans)

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA013328

GENE INFORMATION
Gene name	SYDE1 (HGNC Symbol)
Synonyms	7h3, FLJ13511
Description	Synapse defective 1, Rho GTPase, homolog 1 (C. elegans) (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.12
Chromosome location (bp)	15107403 - 15114988
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105137 (version 83.38)
Entrez gene	85360
UniProt	Q6ZW31 (UniProt - Evidence at protein level)
neXtProt	NX_Q6ZW31
Antibodypedia	SYDE1 antibodies

PROTEIN BROWSER

SYDE1-001	SYDE1-002	SYDE1-003	SYDE1-004	SYDE1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SYDE1-001 ENSP00000341489 ENST00000342784	Q6ZW31 [Direct mapping] Rho GTPase-activating protein SYDE1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005829 [cytosol] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	735 aa 79.8 kDa	No	0
SYDE1-002 ENSP00000470733 ENST00000600440	Q6ZW31 [Direct mapping] Rho GTPase-activating protein SYDE1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005829 [cytosol] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	668 aa 72.9 kDa	No	0
SYDE1-003 ENSP00000469489 ENST00000600252	M0QXZ8 [Direct mapping] Rho GTPase-activating protein SYDE1; Synapse defective 1, Rho GTPase, homolog 1 (C. elegans), isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0007165 [signal transduction] Show all	392 aa 43.4 kDa	No	0
SYDE1-004 ENSP00000473151 ENST00000597977	M0R3D3 [Direct mapping] Rho GTPase-activating protein SYDE1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		170 aa 17.9 kDa	No	0
SYDE1-005 ENSP00000471553 ENST00000602203	M0R101 [Direct mapping] Rho GTPase-activating protein SYDE1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0007165 [signal transduction] Show all	191 aa 20.1 kDa	No	0