Cell atlas - ANKRD27 - The Human Protein Atlas

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ANKRD27

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	ANKRD27
Gene description	Ankyrin repeat domain 27 (VPS9 domain)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (validated)

DATA RELIABILITY
Reliability score	Validated based on 1 antibody. HPA042769
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (validated)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA042769	A-431	Cytosol
	HPA042769	U-2 OS	Cytosol
	HPA042769	U-251 MG	Cytosol

GENE INFORMATION
Gene name	ANKRD27 (HGNC Symbol)
Synonyms	DKFZp434L0718, FLJ00040, VARP
Description	Ankyrin repeat domain 27 (VPS9 domain) (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.11
Chromosome location (bp)	32597007 - 32676597
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105186 (version 83.38)
Entrez gene	84079
UniProt	Q96NW4 (UniProt - Evidence at protein level)
neXtProt	NX_Q96NW4
Antibodypedia	ANKRD27 antibodies

PROTEIN BROWSER

ANKRD27-001	ANKRD27-002	ANKRD27-003	ANKRD27-009	ANKRD27-010	ANKRD27-011	ANKRD27-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANKRD27-001 ENSP00000304292 ENST00000306065	Q96NW4 [Direct mapping] Ankyrin repeat domain-containing protein 27 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000149 [SNARE binding] GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005764 [lysosome] GO:0005769 [early endosome] GO:0005770 [late endosome] GO:0005886 [plasma membrane] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0017137 [Rab GTPase binding] GO:0030133 [transport vesicle] GO:0030659 [cytoplasmic vesicle membrane] GO:0035544 [negative regulation of SNARE complex assembly] GO:0035646 [endosome to melanosome transport] GO:0042470 [melanosome] GO:0043005 [neuron projection] GO:0043547 [positive regulation of GTPase activity] GO:0045022 [early endosome to late endosome transport] GO:0048812 [neuron projection morphogenesis] GO:0050775 [positive regulation of dendrite morphogenesis] GO:0097422 [tubular endosome] GO:1990126 [retrograde transport, endosome to plasma membrane] Show all	1050 aa 117 kDa	No	0
ANKRD27-002 ENSP00000466138 ENST00000587352	K7ELM1 [Direct mapping] Ankyrin repeat domain-containing protein 27 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] Show all	389 aa 44.6 kDa	No	0
ANKRD27-003 ENSP00000467447 ENST00000586463	K7EPM2 [Direct mapping] Ankyrin repeat domain-containing protein 27 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		30 aa 3.4 kDa	No	0
ANKRD27-009 ENSP00000464751 ENST00000591100	K7EIH4 [Direct mapping] Ankyrin repeat domain-containing protein 27 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	174 aa 19.5 kDa	No	0
ANKRD27-010 ENSP00000464819 ENST00000590519	K7EIN0 [Direct mapping] Ankyrin repeat domain-containing protein 27 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		75 aa 8.4 kDa	No	0
ANKRD27-011 ENSP00000476897 ENST00000586693	V9GYL8 [Direct mapping] Ankyrin repeat domain-containing protein 27 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		150 aa 17 kDa	No	0
ANKRD27-201 ENSP00000480730 ENST00000622502	A0A087WX52 [Direct mapping] Ankyrin repeat domain-containing protein 27 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		174 aa 19.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.