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Most malignant cells displayed moderate nuclear staining. Additional cytoplasmic and membranous positivity was observed in cases of colorectal, ovarian, prostate, liver, pancreatic, ovarian, stomach and urothelial cancers. Few cases of colorectal, ovarian, testicular, urothelial and pancreatic cancers were strongly stained. Several malignant lymphomas, endometrial, renal and lung cancers were weakly stained or negative.