Tissue expression of FSD1 - Summary - The Human Protein Atlas

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FSD1

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	FSD1
Gene description	Fibronectin type III and SPRY domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (cerebral cortex, testis)
GTEx:	Group enriched (cerebral cortex, cerebellum, hypothalamus, hippocampus, caudate, testis)
FANTOM5:	Group enriched (cerebellum, hippocampus, caudate, brain, testis)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in CNS and spermatogonia of testis.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 1 antibody. HPA043141
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (cerebral cortex, testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (cerebral cortex, cerebellum, hypothalamus, hippocampus, caudate, testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (cerebellum, hippocampus, caudate, brain, testis)

GENE INFORMATION
Gene name	FSD1 (HGNC Symbol)
Synonyms	MGC3213, MIR1
Description	Fibronectin type III and SPRY domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a centrosome associated protein that is characterized by an N-terminal coiled-coil region downstream of B-box (BBC) domain, a central fibronectin type III domain, and a C-terminal repeats in splA and RyR (SPRY) domain. The encoded protein associates with a subset of microtubules and may be involved in the stability and organization of microtubules during cytokinesis. [provided by RefSeq, Apr 2009]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	4304600 - 4323843
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105255 (version 83.38)
Entrez gene	79187
UniProt	Q9BTV5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BTV5
Antibodypedia	FSD1 antibodies

PROTEIN BROWSER

FSD1-001	FSD1-005	FSD1-006	FSD1-008	FSD1-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FSD1-001 ENSP00000221856 ENST00000221856	Q9BTV5 [Direct mapping] Fibronectin type III and SPRY domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005874 [microtubule] GO:0007067 [mitotic nuclear division] GO:0032154 [cleavage furrow] GO:0051301 [cell division] Show all	496 aa 55.8 kDa	No	0
FSD1-005 ENSP00000473022 ENST00000597590	M0R366 [Direct mapping] Fibronectin type III and SPRY domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] Show all	437 aa 49.2 kDa	No	0
FSD1-006 ENSP00000472060 ENST00000601006	M0R1R0 [Direct mapping] Fibronectin type III and SPRY domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		65 aa 7.5 kDa	No	0
FSD1-008 ENSP00000472521 ENST00000597480	M0R2F6 [Direct mapping] Fibronectin type III and SPRY domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		176 aa 19.4 kDa	No	0
FSD1-011 ENSP00000469629 ENST00000594438	M0QY68 [Direct mapping] Fibronectin type III and SPRY domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	126 aa 13.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.