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CACTIN

CANCER ATLAS

Gene description

 Cactin, spliceosome C complex subunit

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA042504
HPA042548

GENE INFORMATION

Gene name

 CACTIN (HGNC Symbol)

Synonyms

 C19orf29, cactin, fSAPc, NY-REN-24

Description

 Cactin, spliceosome C complex subunit (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.3

Chromosome location (bp)

 3610641 - 3626815

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000105298 (version 83.38)

Entrez gene

 58509

UniProt

 Q8WUQ7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WUQ7

Antibodypedia

 CACTIN antibodies

PROTEIN BROWSER
CACTIN-005
CACTIN-006
CACTIN-007
CACTIN-008
CACTIN-201
CACTIN-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CACTIN-005
ENSP00000467149
ENST00000592721
K7ENY9 [Direct mapping]
Cactin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 291 aa
33.4 kDa 		No 0
CACTIN-006
ENSP00000467788
ENST00000588749
K7EQE3 [Direct mapping]
Cactin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 130 aa
14.7 kDa 		No 0
CACTIN-007
ENSP00000415078
ENST00000429344
Q8WUQ7 [Direct mapping]
Cactin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000398 [mRNA splicing, via spliceosome]
GO:0001933 [negative regulation of protein phosphorylation]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007275 [multicellular organismal development]
GO:0031665 [negative regulation of lipopolysaccharide-mediated signaling pathway]
GO:0032088 [negative regulation of NF-kappaB transcription factor activity]
GO:0032688 [negative regulation of interferon-beta production]
GO:0032717 [negative regulation of interleukin-8 production]
GO:0032720 [negative regulation of tumor necrosis factor production]
GO:0034122 [negative regulation of toll-like receptor signaling pathway]
GO:0044822 [poly(A) RNA binding]
GO:0045087 [innate immune response]
GO:0060339 [negative regulation of type I interferon-mediated signaling pathway]
GO:0070062 [extracellular exosome]
GO:0071013 [catalytic step 2 spliceosome]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071347 [cellular response to interleukin-1]
GO:0071356 [cellular response to tumor necrosis factor]
Show all
 758 aa
88.7 kDa 		No 0
CACTIN-008
ENSP00000464898
ENST00000591726
K7EIU6 [Direct mapping]
Cactin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 117 aa
14.5 kDa 		No 0
CACTIN-201
ENSP00000221899
ENST00000221899
Q8WUQ7 [Direct mapping]
Cactin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000398 [mRNA splicing, via spliceosome]
GO:0001933 [negative regulation of protein phosphorylation]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007275 [multicellular organismal development]
GO:0031665 [negative regulation of lipopolysaccharide-mediated signaling pathway]
GO:0032088 [negative regulation of NF-kappaB transcription factor activity]
GO:0032688 [negative regulation of interferon-beta production]
GO:0032717 [negative regulation of interleukin-8 production]
GO:0032720 [negative regulation of tumor necrosis factor production]
GO:0034122 [negative regulation of toll-like receptor signaling pathway]
GO:0044822 [poly(A) RNA binding]
GO:0045087 [innate immune response]
GO:0060339 [negative regulation of type I interferon-mediated signaling pathway]
GO:0070062 [extracellular exosome]
GO:0071013 [catalytic step 2 spliceosome]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071347 [cellular response to interleukin-1]
GO:0071356 [cellular response to tumor necrosis factor]
Show all
 758 aa
88.7 kDa 		No 0
CACTIN-202
ENSP00000248420
ENST00000248420
Q8WUQ7 [Direct mapping]
Cactin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000398 [mRNA splicing, via spliceosome]
GO:0001933 [negative regulation of protein phosphorylation]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007275 [multicellular organismal development]
GO:0031665 [negative regulation of lipopolysaccharide-mediated signaling pathway]
GO:0032088 [negative regulation of NF-kappaB transcription factor activity]
GO:0032688 [negative regulation of interferon-beta production]
GO:0032717 [negative regulation of interleukin-8 production]
GO:0032720 [negative regulation of tumor necrosis factor production]
GO:0034122 [negative regulation of toll-like receptor signaling pathway]
GO:0044822 [poly(A) RNA binding]
GO:0045087 [innate immune response]
GO:0060339 [negative regulation of type I interferon-mediated signaling pathway]
GO:0070062 [extracellular exosome]
GO:0071013 [catalytic step 2 spliceosome]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071347 [cellular response to interleukin-1]
GO:0071356 [cellular response to tumor necrosis factor]
Show all
 758 aa
88.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.