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Most liver cancers along with several malignant melanomas, renal, testicular and colorectal cancers as well as a few urothelial and gastric cancers showed moderate cytoplasmic positivity in a subset of tumor cells. Remaining cancer tissues were in general negative.
GENE INFORMATION
Gene name
CLEC11A (HGNC Symbol)
Synonyms
CLECSF3, LSLCL, P47, SCGF
Description
C-type lectin domain family 11, member A (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]
Q9Y240 [Direct mapping] C-type lectin domain family 11 member A A0A0A6YY95 [Direct mapping] C-type lectin domain family 11 member A
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Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
