Expression of PLPPR2 in cancer - Summary

CANCER ATLAS

Gene description

Phospholipid phosphatase related 2

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA048973

GENE INFORMATION
Gene name	PLPPR2 (HGNC Symbol)
Synonyms	LPPR2, PRG-4
Description	Phospholipid phosphatase related 2 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	11355386 - 11365698
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105520 (version 83.38)
Entrez gene	64748
UniProt	Q96GM1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96GM1
Antibodypedia	PLPPR2 antibodies

PROTEIN BROWSER

PLPPR2-001	PLPPR2-002	PLPPR2-004	PLPPR2-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PLPPR2-001 ENSP00000251473 ENST00000251473	Q96GM1 [Target identity:100%; Query identity:100%] Lipid phosphate phosphatase-related protein type 2 A0A024R7E2 [Target identity:100%; Query identity:100%] Lipid phosphate phosphatase-related protein type 2, isoform CRA_a Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0008195 [phosphatidate phosphatase activity] GO:0016021 [integral component of membrane] GO:0016311 [dephosphorylation] Show all	343 aa 36.9 kDa	No	6
PLPPR2-002 ENSP00000466898 ENST00000591608		Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all		427 aa 45.6 kDa	No	5
PLPPR2-004 ENSP00000467807 ENST00000591329	K7EQF7 [Direct mapping] Lipid phosphate phosphatase-related protein type 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	85 aa 9.3 kDa	No	1
PLPPR2-006 ENSP00000466698 ENST00000586380	K7EMX8 [Direct mapping] Lipid phosphate phosphatase-related protein type 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		66 aa 7.1 kDa	No	1