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TNPO2

CANCER ATLAS

Gene description

 Transportin 2

Protein class

 Predicted intracellular proteins, Transporters

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
CAB046446

GENE INFORMATION

Gene name

 TNPO2 (HGNC Symbol)

Synonyms

 FLJ12155, IPO3, KPNB2B, TRN2

Description

 Transportin 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.13

Chromosome location (bp)

 12699194 - 12724011

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000105576 (version 83.38)

Entrez gene

 30000

UniProt

 O14787 (UniProt - Evidence at protein level)

neXtProt

 NX_O14787

Antibodypedia

 TNPO2 antibodies

PROTEIN BROWSER
TNPO2-001
TNPO2-002
TNPO2-004
TNPO2-005
TNPO2-009
TNPO2-016
TNPO2-017
TNPO2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TNPO2-001
ENSP00000465625
ENST00000588216
O14787 [Direct mapping]
Transportin-2
A0A024R7F7 [Target identity:100%; Query identity:100%]
Transportin 2 (Importin 3, karyopherin beta 2b), isoform CRA_b
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000059 [protein import into nucleus, docking]
GO:0000060 [protein import into nucleus, translocation]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006607 [NLS-bearing protein import into nucleus]
GO:0006610 [ribosomal protein import into nucleus]
GO:0006886 [intracellular protein transport]
GO:0008139 [nuclear localization sequence binding]
GO:0008536 [Ran GTPase binding]
GO:0008565 [protein transporter activity]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
Show all
 887 aa
100.4 kDa 		No 0
TNPO2-002
ENSP00000468434
ENST00000592287
O14787 [Direct mapping]
Transportin-2
Show all
Transporters
   Transporter channels and pores
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000059 [protein import into nucleus, docking]
GO:0000060 [protein import into nucleus, translocation]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006607 [NLS-bearing protein import into nucleus]
GO:0006610 [ribosomal protein import into nucleus]
GO:0006886 [intracellular protein transport]
GO:0008139 [nuclear localization sequence binding]
GO:0008536 [Ran GTPase binding]
GO:0008565 [protein transporter activity]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
Show all
 897 aa
101.4 kDa 		No 0
TNPO2-004
ENSP00000349321
ENST00000356861
O14787 [Direct mapping]
Transportin-2
A0A024R7F7 [Target identity:100%; Query identity:100%]
Transportin 2 (Importin 3, karyopherin beta 2b), isoform CRA_b
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000059 [protein import into nucleus, docking]
GO:0000060 [protein import into nucleus, translocation]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006607 [NLS-bearing protein import into nucleus]
GO:0006610 [ribosomal protein import into nucleus]
GO:0006886 [intracellular protein transport]
GO:0008139 [nuclear localization sequence binding]
GO:0008536 [Ran GTPase binding]
GO:0008565 [protein transporter activity]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
Show all
 887 aa
100.4 kDa 		No 0
TNPO2-005
ENSP00000397379
ENST00000450764
O14787 [Direct mapping]
Transportin-2
A0A024R7F7 [Target identity:100%; Query identity:100%]
Transportin 2 (Importin 3, karyopherin beta 2b), isoform CRA_b
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000059 [protein import into nucleus, docking]
GO:0000060 [protein import into nucleus, translocation]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006607 [NLS-bearing protein import into nucleus]
GO:0006610 [ribosomal protein import into nucleus]
GO:0006886 [intracellular protein transport]
GO:0008139 [nuclear localization sequence binding]
GO:0008536 [Ran GTPase binding]
GO:0008565 [protein transporter activity]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
Show all
 887 aa
100.4 kDa 		No 0
TNPO2-009
ENSP00000466421
ENST00000590781
K7EMA3 [Direct mapping]
Transportin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 56 aa
6.6 kDa 		No 0
TNPO2-016
ENSP00000467115
ENST00000589337
K7ENW1 [Direct mapping]
Transportin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0008536 [Ran GTPase binding]
Show all
 85 aa
9.9 kDa 		No 0
TNPO2-017
ENSP00000468698
ENST00000589149
K7ESG1 [Direct mapping]
Transportin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 117 aa
13.1 kDa 		No 0
TNPO2-201
ENSP00000407182
ENST00000425528
O14787 [Direct mapping]
Transportin-2
Show all
Transporters
   Transporter channels and pores
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000059 [protein import into nucleus, docking]
GO:0000060 [protein import into nucleus, translocation]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006606 [protein import into nucleus]
GO:0006607 [NLS-bearing protein import into nucleus]
GO:0006610 [ribosomal protein import into nucleus]
GO:0006886 [intracellular protein transport]
GO:0008139 [nuclear localization sequence binding]
GO:0008536 [Ran GTPase binding]
GO:0008565 [protein transporter activity]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
GO:0051148 [negative regulation of muscle cell differentiation]
Show all
 897 aa
101.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.