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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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RAB3A
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    TISSUE

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

RAB3A

Gene description

RAB3A, member RAS oncogene family

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (cerebral cortex)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Selective expression in CNS, islets of Langerhans and adrenal medulla.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

Supported based on 2 antibodies.
HPA003160 , CAB009949
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

RAB3A

Synonyms

Description

RAB3A, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

Chromosome

19

Cytoband

p13.11

Chromosome location (bp)

18196784 - 18204074

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105649 (version 83.38)

Entrez gene

5864

UniProt

P20336 (UniProt - Evidence at protein level)

neXtProt

NX_P20336

Antibodypedia

RAB3A antibodies

PROTEIN BROWSER

RAB3A-001
RAB3A-002
RAB3A-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RAB3A-001
ENSP00000222256
ENST00000222256
P20336 [Direct mapping]
Ras-related protein Rab-3A
A0A024R7I7 [Target identity:100%; Query identity:100%]
H.sapiens ras-related Hrab3A protein; RAB3A, member RAS oncogene family, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001669 [acrosomal vesicle]
GO:0001671 [ATPase activator activity]
GO:0003016 [respiratory system process]
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005768 [endosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006913 [nucleocytoplasmic transport]
GO:0007005 [mitochondrion organization]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007268 [synaptic transmission]
GO:0007269 [neurotransmitter secretion]
GO:0007274 [neuromuscular synaptic transmission]
GO:0007409 [axonogenesis]
GO:0008021 [synaptic vesicle]
GO:0008022 [protein C-terminus binding]
GO:0009306 [protein secretion]
GO:0009791 [post-embryonic development]
GO:0014047 [glutamate secretion]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016188 [synaptic vesicle maturation]
GO:0017157 [regulation of exocytosis]
GO:0030324 [lung development]
GO:0030424 [axon]
GO:0030667 [secretory granule membrane]
GO:0031489 [myosin V binding]
GO:0031630 [regulation of synaptic vesicle fusion to presynaptic membrane]
GO:0032482 [Rab protein signal transduction]
GO:0032781 [positive regulation of ATPase activity]
GO:0036465 [synaptic vesicle recycling]
GO:0043195 [terminal bouton]
GO:0043229 [intracellular organelle]
GO:0043234 [protein complex]
GO:0045054 [constitutive secretory pathway]
GO:0045921 [positive regulation of exocytosis]
GO:0048172 [regulation of short-term neuronal synaptic plasticity]
GO:0048790 [maintenance of presynaptic active zone structure]
GO:0050975 [sensory perception of touch]
GO:0051020 [GTPase binding]
GO:0051117 [ATPase binding]
GO:0051602 [response to electrical stimulus]
GO:0060201 [clathrin-sculpted acetylcholine transport vesicle membrane]
GO:0060203 [clathrin-sculpted glutamate transport vesicle membrane]
GO:0061202 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
GO:0061670 [evoked neurotransmitter secretion]
GO:0070083 [clathrin-sculpted monoamine transport vesicle membrane]
GO:1903307 [positive regulation of regulated secretory pathway]
GO:1903561 [extracellular vesicle]
Show all
220 aa
25 kDa
No 0
RAB3A-002
ENSP00000474603
ENST00000464076
S4R3Q3 [Direct mapping]
Ras-related protein Rab-3A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0009306 [protein secretion]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0030667 [secretory granule membrane]
GO:0032482 [Rab protein signal transduction]
Show all
125 aa
14.1 kDa
No 0
RAB3A-003
ENSP00000472335
ENST00000481914
M0R257 [Direct mapping]
Ras-related protein Rab-3A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005525 [GTP binding]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0007264 [small GTPase mediated signal transduction]
GO:0009306 [protein secretion]
GO:0015031 [protein transport]
GO:0016079 [synaptic vesicle exocytosis]
GO:0030667 [secretory granule membrane]
GO:0032482 [Rab protein signal transduction]
Show all
115 aa
13.3 kDa
No 0

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