Tissue expression of ETV2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ETV2
Gene description	Ets variant 2
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	ETV2 (HGNC Symbol)
Synonyms	ER71
Description	Ets variant 2 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.12
Chromosome location (bp)	35641745 - 35644871
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000105672 (version 83.38)
Entrez gene	2116
UniProt	O00321 (UniProt - Evidence at transcript level)
neXtProt	NX_O00321
Antibodypedia	ETV2 antibodies

PROTEIN BROWSER

ETV2-001	ETV2-003	ETV2-004	ETV2-007	ETV2-008	ETV2-201	ETV2-202	ETV2-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ETV2-001 ENSP00000468453 ENST00000479824	K7ERX2 [Direct mapping] ETS translocation variant 2 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0030154 [cell differentiation] GO:0043565 [sequence-specific DNA binding] Show all	249 aa 26.7 kDa	No	0
ETV2-003 ENSP00000368312 ENST00000379026	O00321 [Direct mapping] ETS translocation variant 2 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0030154 [cell differentiation] GO:0043565 [sequence-specific DNA binding] Show all	370 aa 39.4 kDa	No	0
ETV2-004 ENSP00000385369 ENST00000403402	O00321 [Direct mapping] ETS translocation variant 2 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0030154 [cell differentiation] GO:0043565 [sequence-specific DNA binding] Show all	342 aa 36.6 kDa	No	0
ETV2-007 ENSP00000368309 ENST00000379023	Q3KNT2 [Direct mapping] ETS translocation variant 2; ETV2 protein Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0030154 [cell differentiation] GO:0043565 [sequence-specific DNA binding] Show all	155 aa 17.6 kDa	No	0
ETV2-008 ENSP00000475089 ENST00000591135	S4R454 [Direct mapping] ETS translocation variant 2 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0030154 [cell differentiation] GO:0043565 [sequence-specific DNA binding] Show all	95 aa 10.3 kDa	No	0
ETV2-201 ENSP00000384524 ENST00000402764	O00321 [Direct mapping] ETS translocation variant 2 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0001701 [in utero embryonic development] GO:0001707 [mesoderm formation] GO:0001824 [blastocyst development] GO:0001890 [placenta development] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007219 [Notch signaling pathway] GO:0010628 [positive regulation of gene expression] GO:0016055 [Wnt signaling pathway] GO:0030097 [hemopoiesis] GO:0030154 [cell differentiation] GO:0030218 [erythrocyte differentiation] GO:0043565 [sequence-specific DNA binding] GO:0045603 [positive regulation of endothelial cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048514 [blood vessel morphogenesis] GO:0060803 [BMP signaling pathway involved in mesodermal cell fate specification] GO:2000382 [positive regulation of mesoderm development] Show all	342 aa 36.6 kDa	No	0
ETV2-202 ENSP00000477924 ENST00000619399	A0A087WTJ5 [Direct mapping] ETS translocation variant 2 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0030154 [cell differentiation] Show all	184 aa 19.4 kDa	No	0
ETV2-203 ENSP00000480641 ENST00000621247	A0A087WX03 [Direct mapping] ETS translocation variant 2 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0030154 [cell differentiation] Show all	184 aa 19.3 kDa	No	0