Expression of MOGAT3 in cancer - Summary

CANCER ATLAS

Gene description

Monoacylglycerol O-acyltransferase 3

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA011940

GENE INFORMATION
Gene name	MOGAT3 (HGNC Symbol)
Synonyms	DC7, MGAT3
Description	Monoacylglycerol O-acyltransferase 3 (HGNC Symbol)
Entrez gene summary	Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008]
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	101195007 - 101201021
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000106384 (version 83.38)
Entrez gene	346606
UniProt	Q86VF5 (UniProt - Evidence at protein level)
neXtProt	NX_Q86VF5
Antibodypedia	MOGAT3 antibodies

PROTEIN BROWSER

MOGAT3-001	MOGAT3-002	MOGAT3-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MOGAT3-001 ENSP00000223114 ENST00000223114	Q86VF5 [Direct mapping] 2-acylglycerol O-acyltransferase 3 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003846 [2-acylglycerol O-acyltransferase activity] GO:0004144 [diacylglycerol O-acyltransferase activity] GO:0005789 [endoplasmic reticulum membrane] GO:0006071 [glycerol metabolic process] GO:0016021 [integral component of membrane] GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups] GO:0019432 [triglyceride biosynthetic process] Show all	341 aa 38.7 kDa	No	1
MOGAT3-002 ENSP00000368734 ENST00000379423	Q86VF5 [Direct mapping] 2-acylglycerol O-acyltransferase 3 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003846 [2-acylglycerol O-acyltransferase activity] GO:0004144 [diacylglycerol O-acyltransferase activity] GO:0005789 [endoplasmic reticulum membrane] GO:0006071 [glycerol metabolic process] GO:0016021 [integral component of membrane] GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups] GO:0019432 [triglyceride biosynthetic process] Show all	281 aa 31.5 kDa	No	1
MOGAT3-003 ENSP00000403756 ENST00000440203	Q86VF5 [Direct mapping] 2-acylglycerol O-acyltransferase 3 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003846 [2-acylglycerol O-acyltransferase activity] GO:0004144 [diacylglycerol O-acyltransferase activity] GO:0005789 [endoplasmic reticulum membrane] GO:0006071 [glycerol metabolic process] GO:0016021 [integral component of membrane] GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups] GO:0019432 [triglyceride biosynthetic process] Show all	344 aa 38.4 kDa	No	1