Expression of COA1 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Cytochrome c oxidase assembly factor 1 homolog

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA011944

GENE INFORMATION
Gene name	COA1 (HGNC Symbol)
Synonyms	C7orf44, FLJ10803, MITRAC15
Description	Cytochrome c oxidase assembly factor 1 homolog (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	p13
Chromosome location (bp)	43608456 - 43729717
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000106603 (version 83.38)
Entrez gene	55744
UniProt	Q9GZY4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9GZY4
Antibodypedia	COA1 antibodies

PROTEIN BROWSER

COA1-003	COA1-004	COA1-013	COA1-015	COA1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COA1-003 ENSP00000312100 ENST00000310564	Q9GZY4 [Direct mapping] Cytochrome c oxidase assembly factor 1 homolog A0A024RA60 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005840 [ribosome] GO:0006412 [translation] GO:0031305 [integral component of mitochondrial inner membrane] GO:0032981 [mitochondrial respiratory chain complex I assembly] GO:0033617 [mitochondrial respiratory chain complex IV assembly] Show all	146 aa 16.7 kDa	No	1
COA1-004 ENSP00000379218 ENST00000395879	Q9GZY4 [Direct mapping] Cytochrome c oxidase assembly factor 1 homolog A0A024RA60 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005840 [ribosome] GO:0006412 [translation] GO:0031305 [integral component of mitochondrial inner membrane] GO:0032981 [mitochondrial respiratory chain complex I assembly] GO:0033617 [mitochondrial respiratory chain complex IV assembly] Show all	146 aa 16.7 kDa	No	1
COA1-013 ENSP00000405582 ENST00000415798	C9JA07 [Direct mapping] Cytochrome c oxidase assembly factor 1 homolog Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005840 [ribosome] GO:0006412 [translation] GO:0016021 [integral component of membrane] Show all	113 aa 12.8 kDa	No	1
COA1-015 ENSP00000417046 ENST00000431651	C9J6J1 [Direct mapping] Cytochrome c oxidase assembly factor 1 homolog Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005840 [ribosome] GO:0006412 [translation] GO:0016021 [integral component of membrane] Show all	88 aa 10.2 kDa	No	1
COA1-201 ENSP00000223336 ENST00000223336	Q9GZY4 [Direct mapping] Cytochrome c oxidase assembly factor 1 homolog A0A024RA60 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005840 [ribosome] GO:0006412 [translation] GO:0031305 [integral component of mitochondrial inner membrane] GO:0032981 [mitochondrial respiratory chain complex I assembly] GO:0033617 [mitochondrial respiratory chain complex IV assembly] Show all	146 aa 16.7 kDa	No	1