Expression of C10orf54 in cancer - Summary - The Human Protein Atlas

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C10orf54

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Chromosome 10 open reading frame 54

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA007968

GENE INFORMATION
Gene name	C10orf54 (HGNC Symbol)
Synonyms	B7-H5, B7H5, GI24, SISP1, VISTA
Description	Chromosome 10 open reading frame 54 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q22.1
Chromosome location (bp)	71747559 - 71773498
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000107738 (version 83.38)
Entrez gene	64115
UniProt	Q9H7M9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H7M9
Antibodypedia	C10orf54 antibodies

PROTEIN BROWSER

C10orf54-001	C10orf54-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C10orf54-001 ENSP00000378409 ENST00000394957	Q9H7M9 [Direct mapping] Platelet receptor Gi24 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002725 [negative regulation of T cell cytokine production] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0009897 [external side of plasma membrane] GO:0016021 [integral component of membrane] GO:0030509 [BMP signaling pathway] GO:0030513 [positive regulation of BMP signaling pathway] GO:0048863 [stem cell differentiation] GO:2000562 [negative regulation of CD4-positive, alpha-beta T cell proliferation] GO:2000738 [positive regulation of stem cell differentiation] Show all	311 aa 33.9 kDa	Yes	1
C10orf54-003 ENSP00000473568 ENST00000470317	R4GNB4 [Direct mapping] Platelet receptor Gi24 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	140 aa 14.8 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.