Expression of LZTS2 in cancer - Summary

CANCER ATLAS

Gene description

Leucine zipper, putative tumor suppressor 2

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA044956

GENE INFORMATION
Gene name	LZTS2 (HGNC Symbol)
Synonyms	KIAA1813, LAPSER1
Description	Leucine zipper, putative tumor suppressor 2 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q24.31
Chromosome location (bp)	100996618 - 101007836
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000107816 (version 83.38)
Entrez gene	84445
UniProt	Q9BRK4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BRK4
Antibodypedia	LZTS2 antibodies

PROTEIN BROWSER

LZTS2-001	LZTS2-002	LZTS2-004	LZTS2-006	LZTS2-007	LZTS2-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LZTS2-001 ENSP00000359240 ENST00000370220	Q9BRK4 [Direct mapping] Leucine zipper putative tumor suppressor 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000910 [cytokinesis] GO:0001822 [kidney development] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005874 [microtubule] GO:0007067 [mitotic nuclear division] GO:0008285 [negative regulation of cell proliferation] GO:0010942 [positive regulation of cell death] GO:0016055 [Wnt signaling pathway] GO:0030178 [negative regulation of Wnt signaling pathway] GO:0030496 [midbody] GO:0051013 [microtubule severing] GO:0051168 [nuclear export] GO:0051255 [spindle midzone assembly] GO:0072001 [renal system development] GO:0090090 [negative regulation of canonical Wnt signaling pathway] GO:1900181 [negative regulation of protein localization to nucleus] Show all	669 aa 72.8 kDa	No	0
LZTS2-002 ENSP00000359243 ENST00000370223	Q9BRK4 [Direct mapping] Leucine zipper putative tumor suppressor 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000910 [cytokinesis] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005874 [microtubule] GO:0007067 [mitotic nuclear division] GO:0030496 [midbody] GO:0051013 [microtubule severing] GO:0051168 [nuclear export] GO:0051255 [spindle midzone assembly] Show all	669 aa 72.8 kDa	No	0
LZTS2-004 ENSP00000407713 ENST00000426584	B1AL13 [Direct mapping] Leucine zipper putative tumor suppressor 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		240 aa 24.7 kDa	No	0
LZTS2-006 ENSP00000416972 ENST00000454422	B1AL12 [Direct mapping] Leucine zipper putative tumor suppressor 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		221 aa 22.8 kDa	No	0
LZTS2-007 ENSP00000402042 ENST00000429732	B1AL11 [Direct mapping] Leucine zipper putative tumor suppressor 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		199 aa 20.7 kDa	No	0
LZTS2-008 ENSP00000474819 ENST00000481129	S4R3W7 [Direct mapping] Leucine zipper putative tumor suppressor 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		136 aa 14.4 kDa	No	0