Expression of KAZALD1 in cancer - Summary

CANCER ATLAS

Gene description

Kazal-type serine peptidase inhibitor domain 1

Protein class

Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA011800

GENE INFORMATION
Gene name	KAZALD1 (HGNC Symbol)
Synonyms	FKSG28, FKSG40
Description	Kazal-type serine peptidase inhibitor domain 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. It contains an N-terminal insulin growth factor-binding domain, a central Kazal-type serine protease inhibitor and follistatin-like domain, and a C-terminal immunoglobulin-like domain. Studies of the mouse ortholog suggest that this gene product may have a function in bone development and bone regeneration. [provided by RefSeq, Feb 2009]
Chromosome	10
Cytoband	q24.31
Chromosome location (bp)	101061841 - 101068131
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000107821 (version 83.38)
Entrez gene	81621
UniProt	Q96I82 (UniProt - Evidence at protein level)
neXtProt	NX_Q96I82
Antibodypedia	KAZALD1 antibodies

PROTEIN BROWSER

KAZALD1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KAZALD1-001 ENSP00000359219 ENST00000370200	Q96I82 [Direct mapping] Kazal-type serine protease inhibitor domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0001503 [ossification] GO:0001558 [regulation of cell growth] GO:0005515 [protein binding] GO:0005520 [insulin-like growth factor binding] GO:0005576 [extracellular region] GO:0005578 [proteinaceous extracellular matrix] GO:0005614 [interstitial matrix] GO:0007275 [multicellular organismal development] GO:0030154 [cell differentiation] GO:0030198 [extracellular matrix organization] Show all	304 aa 32.9 kDa	Yes	0