Tissue expression of ACBD5 - Summary - The Human Protein Atlas

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ACBD5

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TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ACBD5
Gene description	Acyl-CoA binding domain containing 5
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA011861 , HPA012145
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ACBD5 (HGNC Symbol)
Synonyms	DKFZp434A2417, KIAA1996
Description	Acyl-CoA binding domain containing 5 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the acyl-Coenzyme A binding protein family, known to function in the transport and distribution of long chain acyl-Coenzyme A in cells. This gene may play a role in the differentiation of megakaryocytes and formation of platelets. A related protein in yeast is involved in autophagy of peroxisomes. A mutation in this gene has been associated with autosomal dominant thrombocytopenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Chromosome	10
Cytoband	p12.1
Chromosome location (bp)	27195214 - 27242130
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000107897 (version 83.38)
Entrez gene	91452
UniProt	Q5T8D3 (UniProt - Evidence at protein level)
neXtProt	NX_Q5T8D3
Antibodypedia	ACBD5 antibodies

PROTEIN BROWSER

ACBD5-001	ACBD5-002	ACBD5-003	ACBD5-005	ACBD5-006	ACBD5-007	ACBD5-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACBD5-001 ENSP00000379568 ENST00000396271	Q5T8D3 [Direct mapping] Acyl-CoA-binding domain-containing protein 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0003674 [molecular_function] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005777 [peroxisome] GO:0005778 [peroxisomal membrane] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030242 [pexophagy] GO:0043231 [intracellular membrane-bounded organelle] Show all	525 aa 59 kDa	No	1
ACBD5-002 ENSP00000365070 ENST00000375905	Q5T8D3 [Direct mapping] Acyl-CoA-binding domain-containing protein 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0003674 [molecular_function] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005777 [peroxisome] GO:0005778 [peroxisomal membrane] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030242 [pexophagy] GO:0043231 [intracellular membrane-bounded organelle] Show all	490 aa 54.8 kDa	No	1
ACBD5-003 ENSP00000365066 ENST00000375901	Q5T8D3 [Direct mapping] Acyl-CoA-binding domain-containing protein 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0003674 [molecular_function] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005777 [peroxisome] GO:0005778 [peroxisomal membrane] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030242 [pexophagy] GO:0043231 [intracellular membrane-bounded organelle] Show all	416 aa 46.3 kDa	No	1
ACBD5-005 ENSP00000365049 ENST00000375888	Q5T8D3 [Direct mapping] Acyl-CoA-binding domain-containing protein 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0003674 [molecular_function] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005777 [peroxisome] GO:0005778 [peroxisomal membrane] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030242 [pexophagy] GO:0043231 [intracellular membrane-bounded organelle] Show all	534 aa 60.1 kDa	No	1
ACBD5-006 ENSP00000401591 ENST00000426079	Q5T8E0 [Direct mapping] Acyl-CoA-binding domain-containing protein 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] Show all	252 aa 28.2 kDa	No	0
ACBD5-007 ENSP00000393398 ENST00000412279	X6RDD7 [Direct mapping] Acyl-CoA-binding domain-containing protein 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] Show all	251 aa 28.1 kDa	No	0
ACBD5-201 ENSP00000365062 ENST00000375897	B7Z2R7 [Direct mapping] Acyl-CoA-binding domain-containing protein 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0016021 [integral component of membrane] Show all	523 aa 58.8 kDa	No	1

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.