Cell atlas - SLC25A11 - The Human Protein Atlas

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SLC25A11

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SLC25A11
Gene description	Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
Protein class	Plasma proteins Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SLC25A11 (HGNC Symbol)
Synonyms	OGC, SLC20A4
Description	Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 (HGNC Symbol)
Entrez gene summary	The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).[supplied by OMIM, Jan 2011]
Chromosome	17
Cytoband	p13.2
Chromosome location (bp)	4937130 - 4940251
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000108528 (version 83.38)
Entrez gene	8402
UniProt	Q02978 (UniProt - Evidence at protein level)
neXtProt	NX_Q02978
Antibodypedia	SLC25A11 antibodies

PROTEIN BROWSER

SLC25A11-001	SLC25A11-003	SLC25A11-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC25A11-001 ENSP00000225665 ENST00000225665	Q02978 [Direct mapping] Mitochondrial 2-oxoglutarate/malate carrier protein Q6IBH0 [Target identity:100%; Query identity:100%] SLC25A11 protein; Solute carrier family 25 (Mitochondrial carrier oxoglutarate carrier), member 11, isoform CRA_b; cDNA FLJ76014, highly similar to Homo sapiens solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 (SLC25A11), mRNA Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005887 [integral component of plasma membrane] GO:0005975 [carbohydrate metabolic process] GO:0006006 [glucose metabolic process] GO:0006094 [gluconeogenesis] GO:0006810 [transport] GO:0015367 [oxoglutarate:malate antiporter activity] GO:0015742 [alpha-ketoglutarate transport] GO:0044281 [small molecule metabolic process] GO:0044822 [poly(A) RNA binding] Show all	314 aa 34.1 kDa	No	1
SLC25A11-003 ENSP00000440804 ENST00000544061	Q02978 [Direct mapping] Mitochondrial 2-oxoglutarate/malate carrier protein Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005887 [integral component of plasma membrane] GO:0005975 [carbohydrate metabolic process] GO:0006006 [glucose metabolic process] GO:0006094 [gluconeogenesis] GO:0006810 [transport] GO:0015367 [oxoglutarate:malate antiporter activity] GO:0015742 [alpha-ketoglutarate transport] GO:0044281 [small molecule metabolic process] GO:0044822 [poly(A) RNA binding] Show all	263 aa 28.5 kDa	No	1
SLC25A11-004 ENSP00000458993 ENST00000576951	I3L1P8 [Direct mapping] Mitochondrial 2-oxoglutarate/malate carrier protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0016021 [integral component of membrane] Show all	296 aa 32.2 kDa	No	1

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.