Tissue expression of MMD - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	MMD
Gene description	Monocyte to macrophage differentiation-associated
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (adipose tissue)
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (adipose tissue)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	MMD (HGNC Symbol)
Synonyms	MMA, PAQR11
Description	Monocyte to macrophage differentiation-associated (HGNC Symbol)
Entrez gene summary	This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q22
Chromosome location (bp)	55392613 - 55421992
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000108960 (version 83.38)
Entrez gene	23531
UniProt	Q15546 (UniProt - Evidence at transcript level)
neXtProt	NX_Q15546
Antibodypedia	MMD antibodies

PROTEIN BROWSER

MMD-001	MMD-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MMD-001 ENSP00000262065 ENST00000262065	Q15546 [Direct mapping] Monocyte to macrophage differentiation factor Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004672 [protein kinase activity] GO:0004872 [receptor activity] GO:0005765 [lysosomal membrane] GO:0005794 [Golgi apparatus] GO:0005887 [integral component of plasma membrane] GO:0006468 [protein phosphorylation] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019835 [cytolysis] GO:0031902 [late endosome membrane] GO:0032880 [regulation of protein localization] GO:0045666 [positive regulation of neuron differentiation] GO:0045860 [positive regulation of protein kinase activity] Show all	238 aa 27.7 kDa	No	7
MMD-003 ENSP00000459202 ENST00000571578	I3L1Y1 [Direct mapping] Monocyte to macrophage differentiation factor Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	147 aa 17.2 kDa	No	4