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Most of the cancer tissues displayed weak to moderate cytoplasmic positivity. Several cases of melanomas, ovarian, skin and liver cancers were negative.
GENE INFORMATION
Gene name
RANGRF (HGNC Symbol)
Synonyms
HSPC165, HSPC236, MOG1, RANGNRF
Description
RAN guanine nucleotide release factor (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]