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RCVRN

CANCER ATLAS

Gene description

 Recoverin

Protein class

 Plasma proteins, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA015783
CAB022363

GENE INFORMATION

Gene name

 RCVRN (HGNC Symbol)

Synonyms

 RCV1

Description

 Recoverin (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq, Jul 2008]

Chromosome

 17

Cytoband

 p13.1

Chromosome location (bp)

 9896320 - 9905621

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000109047 (version 83.38)

Entrez gene

 5957

UniProt

 P35243 (UniProt - Evidence at protein level)

neXtProt

 NX_P35243

Antibodypedia

 RCVRN antibodies

PROTEIN BROWSER
RCVRN-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RCVRN-001
ENSP00000226193
ENST00000226193
P35243 [Direct mapping]
Recoverin
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0007165 [signal transduction]
GO:0007601 [visual perception]
GO:0007602 [phototransduction]
GO:0007603 [phototransduction, visible light]
GO:0008048 [calcium sensitive guanylate cyclase activator activity]
GO:0016056 [rhodopsin mediated signaling pathway]
GO:0022400 [regulation of rhodopsin mediated signaling pathway]
GO:0031284 [positive regulation of guanylate cyclase activity]
GO:0051924 [regulation of calcium ion transport]
Show all
 200 aa
23.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.