Expression of SNX25 in cancer - Summary

CANCER ATLAS

Gene description

Sorting nexin 25

Protein class

Cancer-related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA036928

GENE INFORMATION
Gene name	SNX25 (HGNC Symbol)
Synonyms	SBBI31
Description	Sorting nexin 25 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	q35.1
Chromosome location (bp)	185204237 - 185370185
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000109762 (version 83.38)
Entrez gene	83891
UniProt	Q9H3E2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H3E2
Antibodypedia	SNX25 antibodies

PROTEIN BROWSER

SNX25-001	SNX25-004	SNX25-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SNX25-001 ENSP00000426255 ENST00000504273	Q9H3E2 [Direct mapping] Sorting nexin-25 Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005768 [endosome] GO:0010008 [endosome membrane] GO:0015031 [protein transport] GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] GO:0032801 [receptor catabolic process] GO:0034713 [type I transforming growth factor beta receptor binding] GO:0035091 [phosphatidylinositol binding] GO:0060394 [negative regulation of pathway-restricted SMAD protein phosphorylation] Show all	840 aa 97.9 kDa	No	0
SNX25-004 ENSP00000264694 ENST00000264694	Q9H3E2 [Direct mapping] Sorting nexin-25 Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0010008 [endosome membrane] GO:0015031 [protein transport] GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] GO:0032801 [receptor catabolic process] GO:0035091 [phosphatidylinositol binding] GO:0060394 [negative regulation of pathway-restricted SMAD protein phosphorylation] Show all	840 aa 97.9 kDa	No	0
SNX25-201 ENSP00000483653 ENST00000618785	Q9H3E2 [Direct mapping] Sorting nexin-25 Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0010008 [endosome membrane] GO:0015031 [protein transport] GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] GO:0032801 [receptor catabolic process] GO:0035091 [phosphatidylinositol binding] GO:0060394 [negative regulation of pathway-restricted SMAD protein phosphorylation] Show all	556 aa 64.8 kDa	No	0