Cell atlas - KLF3 - The Human Protein Atlas

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KLF3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	KLF3
Gene description	Kruppel-like factor 3 (basic)
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)
Mouse	Localized to the Nucleus in mouse cells.

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA049512 , HPA065054
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ASSAYS

RNA expression

Human cells

Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (supported)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA049512	A-431	Nucleoplasm
HPA049512	RT4	Nucleoplasm
HPA049512	U-2 OS	Nucleoplasm
HPA065054	RT4	Nucleoplasm
HPA065054	U-2 OS	Nucleoplasm

MOUSE CELLS

Main location

Nucleus

Mouse gene

ENSMUSG00000029178 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA049512	NIH 3T3	Nucleus

GENE INFORMATION
Gene name	KLF3 (HGNC Symbol)
Synonyms	BKLF
Description	Kruppel-like factor 3 (basic) (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	p14
Chromosome location (bp)	38664196 - 38701042
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000109787 (version 83.38)
Entrez gene	51274
UniProt	P57682 (UniProt - Evidence at protein level)
neXtProt	NX_P57682
Antibodypedia	KLF3 antibodies

PROTEIN BROWSER

KLF3-001	KLF3-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KLF3-001 ENSP00000261438 ENST00000261438	P57682 [Direct mapping] Krueppel-like factor 3 A0A024R9T8 [Target identity:100%; Query identity:100%] Kruppel-like factor 3 (Basic), isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0046872 [metal ion binding] GO:1901653 [cellular response to peptide] Show all	345 aa 38.8 kDa	No	0
KLF3-002 ENSP00000421252 ENST00000514033	P57682 [Direct mapping] Krueppel-like factor 3 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0046872 [metal ion binding] Show all	232 aa 25.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.